{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T13:34:39Z","timestamp":1786714479080,"version":"build-2736575974"},"reference-count":39,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T00:00:00Z","timestamp":1780963200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T00:00:00Z","timestamp":1780963200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Pulsed\u2010field ablation (PFA) has transformed atrial fibrillation (AF) ablation, but how the early patient experience compares with thermal techniques remains unclear. This study aimed to assess patient\u2010reported outcome measures (PROMs) in the first 3 months after PFA or thermal AF ablation, using a novel smartphone\u2010based application.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients undergoing first\u2010time pulmonary vein isolation prospectively completed the Cardiac Ablation Recovery Evaluation (CARE) symptom questionnaire at five timepoints: baseline, day 1, day 7, day 30, and day 90. Symptoms were rated on a 7\u2010point Likert scale (0\u2009=\u2009not at all; 6\u2009=\u2009extremely). Patients also completed the Atrial Fibrillation Effect on QualiTy\u2010of\u2010life (AFEQT) questionnaire at baseline and day 90.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Two hundred and two patients were included (pentaspline PFA: 66; radiofrequency: 64; cryoballoon: 72), with similar baseline demographics between groups, except for a lower prevalence of paroxysmal AF in the PFA group. Engagement with the smartphone\u2010based platform was high, with a 94.7% completion rate. Median AFEQT scores improved from 64 (47\u201382) at baseline to 86 (72\u201395) at day 90 (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), with no significant differences between modalities (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.841). However, CARE detected differences in early symptom experience: chest pain was lowest with PFA at day 1 (median: PFA, 1 [0\u20132]; radiofrequency, 2 [1\u20132]; cryoballoon, 2 [1\u20132];\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), and remained lower than cryoballoon at day 7 (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.019), with differences resolving by day 30. Moderate\u2010to\u2010severe chest pain (score \u2265\u20093) occurred in only 12.3% of PFA patients at day 1, compared with 21.2% cryoballoon and 26.2% radiofrequency patients (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Palpitations at day 1 were less frequent with PFA than radiofrequency (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.040). Groin discomfort was lower with radiofrequency than PFA or cryoballoon at day 1 (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.006) and day 7 (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), likely reflecting a smaller sheath size.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>PFA was associated with a modest and transient reduction in early post\u2010procedural chest pain compared with thermal ablation. Smartphone application\u2010based PROMs collection using the CARE questionnaire was feasible, enabling structured assessment of symptom burden across multiple recovery timepoints.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jce.70392","type":"journal-article","created":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T14:11:24Z","timestamp":1781014284000},"page":"1685-1698","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Patient\u2010Reported Outcome Measures Following Pulsed\u2010Field Ablation Versus Thermal Ablation of Atrial Fibrillation: The PROMs\u2010PFA Study"],"prefix":"10.1111","volume":"37","author":[{"given":"Mark T.","family":"Mills","sequence":"first","affiliation":[{"name":"Department of Cardiology Liverpool Heart &amp; Chest Hospital Liverpool Merseyside UK"},{"name":"Liverpool Centre for Cardiovascular Science at University of Liverpool Liverpool John Moores University and Liverpool Heart &amp; Chest Hospital Liverpool Merseyside UK"},{"name":"Department of Cardiology Sheffield Teaching Hospitals NHS Foundation Trust Sheffield South Yorkshire UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8401-4033","authenticated-orcid":false,"given":"Peter","family":"Calvert","sequence":"additional","affiliation":[{"name":"Department of Cardiology Liverpool Heart &amp; Chest Hospital Liverpool Merseyside UK"},{"name":"Liverpool Centre for Cardiovascular Science at University of Liverpool Liverpool John Moores University and Liverpool Heart &amp; Chest Hospital Liverpool Merseyside UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keith","family":"Wilson","sequence":"additional","affiliation":[{"name":"Research Department, Liverpool Heart &amp; Chest Hospital Liverpool Merseyside UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zoltan","family":"Borbas","sequence":"additional","affiliation":[{"name":"Department of Cardiology Liverpool Heart &amp; Chest Hospital Liverpool Merseyside UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Snowdon","sequence":"additional","affiliation":[{"name":"Department of Cardiology Liverpool Heart &amp; Chest Hospital Liverpool Merseyside UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saagar N.","family":"Mahida","sequence":"additional","affiliation":[{"name":"Department of Cardiology Liverpool Heart &amp; Chest Hospital Liverpool Merseyside UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reza","family":"Ashrafi","sequence":"additional","affiliation":[{"name":"Department of Cardiology Liverpool Heart &amp; Chest Hospital Liverpool Merseyside UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johan","family":"Waktare","sequence":"additional","affiliation":[{"name":"Department of Cardiology Liverpool Heart &amp; Chest Hospital Liverpool Merseyside UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Modi","sequence":"additional","affiliation":[{"name":"Department of Cardiology Liverpool Heart &amp; Chest Hospital Liverpool Merseyside UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Derick","family":"Todd","sequence":"additional","affiliation":[{"name":"Department of Cardiology Liverpool Heart &amp; Chest Hospital Liverpool Merseyside UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathan","family":"Denham","sequence":"additional","affiliation":[{"name":"Department of Cardiology Liverpool Heart &amp; Chest Hospital Liverpool Merseyside UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3274-7128","authenticated-orcid":false,"given":"Vishal","family":"Luther","sequence":"additional","affiliation":[{"name":"Department of Cardiology Liverpool Heart &amp; Chest Hospital Liverpool Merseyside UK"},{"name":"Liverpool Centre for Cardiovascular Science at University of Liverpool Liverpool John Moores University and Liverpool Heart &amp; Chest Hospital Liverpool Merseyside UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dhiraj","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Cardiology Liverpool Heart &amp; 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