{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T13:34:44Z","timestamp":1786714484533,"version":"build-2736575974"},"reference-count":16,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T00:00:00Z","timestamp":1781481600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T00:00:00Z","timestamp":1781481600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>New\u2010onset migraine or exacerbation of pre\u2010existent migraine has been reported following catheter ablation for atrial fibrillation (AF). We assessed the incidence of migraine following pulsed\u2010field ablation (PFA).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Consecutive AF patients undergoing PFA using either Farawave or Pulse Select or Sphere 9 catheter systems were included in this multicenter study and prospectively followed up for new migraine or an increase in the severity of the pre\u2010existent headache. Migraine was labeled as \u201cnew onset\u201d if the condition was diagnosed for the first time after the index ablation without any previous history, recent or remote. Anti\u2010arrhythmic drugs and oral anticoagulation were prescribed for 2 months after the procedure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 2148 AF patients undergoing PFA procedures (Farawave: 1477; Pulse Select: 369; and Sphere 9: 392) at the participating centers were included in the analysis. A history of migraine was present in 32 (1.48%) patients, of which 6(18.75%) reported an increase in frequency of migraine in the immediate post\u2010ablation period. New\u2010onset migraine was diagnosed in 31 (1.4%) post\u2010PFA patients. Of these 31 patients, 25 (80.6%) underwent PFA using the Farapulse system, Sphere 9 in 5 (16.12%), and Pulse Select in 1 (3.22%) patient. The incidence of new\u2010onset migraine was comparable between different systems; 1.69% (95% CI 1.10%\u22122.49%), 1.65% (95% CI 0.54%\u22123.82%), and 0.27% (95% CI 0.01%\u22121.50%) for Farapulse, Sphere 9, and Pulse Select, respectively. Mean duration of onset was 3.08\u2009\u00b1\u20090.67 days post\u2010procedure. In the multivariable regression analysis, BMI was found to be the only predictor of new\u2010onset migraine (OR\u2009=\u20091.402; 95% CI 1.002\u20131.987;\n                      <jats:italic>p<\/jats:italic>\n                      \u2010value\u2009=\u20090.031).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>New\u2010onset migraine was observed to be uncommon in patients undergoing PFA. Although the incidence rate was comparable among the three platforms analyzed, the Farawave system showed a higher trend. Of note, BMI was an independent predictor of new migraine.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jce.70399","type":"journal-article","created":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T18:41:19Z","timestamp":1781548879000},"page":"1740-1745","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Incidence of Migraine Following Pulsed\u2010Field Ablation for Atrial Fibrillation: Findings From a Multicenter Analysis"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6601-944X","authenticated-orcid":false,"given":"Sanghamitra","family":"Mohanty","sequence":"first","affiliation":[{"name":"Texas Cardiac Arrhythmia Institute St. David's Medical Center Austin Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaariv","family":"Khaykin","sequence":"additional","affiliation":[{"name":"Southlake Health Newmarket Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mouhannad","family":"Sadek","sequence":"additional","affiliation":[{"name":"Southlake Health Newmarket Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfredo","family":"Pantano","sequence":"additional","affiliation":[{"name":"Southlake Health Newmarket Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"PremGeeta","family":"Torlapati","sequence":"additional","affiliation":[{"name":"Texas Cardiac Arrhythmia Institute St. David's Medical Center Austin Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7548-4685","authenticated-orcid":false,"given":"Vincenzo Mirco La","family":"Fazia","sequence":"additional","affiliation":[{"name":"Texas Cardiac Arrhythmia Institute St. David's Medical Center Austin Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carola","family":"Gianni","sequence":"additional","affiliation":[{"name":"Texas Cardiac Arrhythmia Institute St. David's Medical Center Austin Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bryan","family":"MacDonald","sequence":"additional","affiliation":[{"name":"Texas Cardiac Arrhythmia Institute St. David's Medical Center Austin Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angel","family":"Mayedo","sequence":"additional","affiliation":[{"name":"Texas Cardiac Arrhythmia Institute St. David's Medical Center Austin Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8547-025X","authenticated-orcid":false,"given":"Amin","family":"Al\u2010Ahmad","sequence":"additional","affiliation":[{"name":"Texas Cardiac Arrhythmia Institute St. David's Medical Center Austin Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John D.","family":"Burkhardt","sequence":"additional","affiliation":[{"name":"Texas Cardiac Arrhythmia Institute St. David's Medical Center Austin Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. J.","family":"Gallinghouse","sequence":"additional","affiliation":[{"name":"Texas Cardiac Arrhythmia Institute St. David's Medical Center Austin Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodney","family":"Horton","sequence":"additional","affiliation":[{"name":"Texas Cardiac Arrhythmia Institute St. David's Medical Center Austin Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Allison","sequence":"additional","affiliation":[{"name":"Texas Cardiac Arrhythmia Institute St. David's Medical Center Austin Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weeranun","family":"Bode","sequence":"additional","affiliation":[{"name":"Texas Cardiac Arrhythmia Institute St. David's Medical Center Austin Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6508-4047","authenticated-orcid":false,"given":"Luigi Di","family":"Biase","sequence":"additional","affiliation":[{"name":"Department of Electrophysiology Albert Einstein College of Medicine at Montefiore Hospital Bronx New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Natale","sequence":"additional","affiliation":[{"name":"Texas Cardiac Arrhythmia Institute St. David's Medical Center Austin Texas USA"},{"name":"Interventional Electrophysiology Scripps Clinic San Diego California USA"},{"name":"Metro Health Medical Center Case Western Reserve University School of Medicine Cleveland Ohio USA"},{"name":"Department of Biomedicine and Prevention Division of Cardiology University of Tor Vergata Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,15]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.114.002285"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000201699"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2009.01525.x"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2009.01430.x"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-010-9519-z"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2025.06.035"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrcardio.2015.26"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(25)00665-5"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/ene.15198"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2022.10.028"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2024.05.005"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2023.05.035"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000003919"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2021.111557"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph19010362"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2020.106019"}],"container-title":["Journal of Cardiovascular Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jce.70399","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jce.70399","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jce.70399","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T12:57:29Z","timestamp":1786712249000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jce.70399"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,15]]},"references-count":16,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["10.1111\/jce.70399"],"URL":"https:\/\/doi.org\/10.1111\/jce.70399","archive":["Portico"],"relation":{},"ISSN":["1045-3873","1540-8167"],"issn-type":[{"value":"1045-3873","type":"print"},{"value":"1540-8167","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,15]]},"assertion":[{"value":"2025-11-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-02","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}