{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T13:34:37Z","timestamp":1786714477686,"version":"build-2736575974"},"reference-count":9,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T00:00:00Z","timestamp":1782172800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T00:00:00Z","timestamp":1782172800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Although the implantable cardioverter defibrillators (ICD) are the only established treatment to prevent sudden cardiac death, previous studies reported that those who receive shock therapies, whether appropriate or inappropriate, have a higher risk of death. However, the difference in the influence of shock therapies between via Transvenous\u2010ICD (TV\u2010ICD) and Subcutaneous\u2010ICD (S\u2010ICD) has not been adequately examined. We aimed to investigate the influence of shocks on myocardium in patients with TV\u2010ICD and S\u2010ICD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We enrolled consecutive patients who received a defibrillator or transvenous pacemaker (TV\u2010PM) implantation between November 2020 and March 2024. A total of 74 patients were included in this study and divided into three groups: patients with TV\u2010ICD with defibrillation testing (DFT) (TV\u2010DFT, 27 patients), those with transvenous devices implanted without DFT (TV\u2010no DFT, 25 patients) and those with S\u2010ICD (22 patients).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Delta log troponin\u2010I (the difference of serum troponin\u2010I levels between baseline and after implantation) was significantly increased in TV\u2010DFT group. In patients with TV\u2010ICD (46 patients), Delta log troponin\u2010I was significantly correlated with total shock joules. In the multivariable linear regression analysis, a value of total shock joules was independently associated with delta troponin\u2010I.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Elevation of serum troponin\u2010I was associated with the TV\u2010ICD shocks and correlated with the total shock energy, but not with S\u2010ICD shocks. Our results suggest that TV\u2010ICD shocks are associated with greater myocardial injury compared to S\u2010ICD shocks, and that total shock energy is an important determinant of the extent of myocardial damage.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jce.70419","type":"journal-article","created":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T18:46:04Z","timestamp":1782240364000},"page":"1793-1800","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Different Effects of Defibrillator Shocks on the Myocardial Damage Between Subcutaneous and Transvenous Implantable Cardioverter\u2010Defibrillators"],"prefix":"10.1111","volume":"37","author":[{"given":"Takahide","family":"Kadosaka","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine Hokkaido University Sapporo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0757-9601","authenticated-orcid":false,"given":"Masaya","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine Hokkaido University Sapporo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Motoki","family":"Nakao","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine Hokkaido University Sapporo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2154-4587","authenticated-orcid":false,"given":"Taro","family":"Koya","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine Hokkaido University Sapporo 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Cardiovascular Medicine, Japan Community Health care Organization Hokkaido Hospital Sapporo Japan"},{"name":"Department of Cardiovascular Medicine Sunagawa City Medical Center Sunagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hisashi","family":"Yokoshiki","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Sapporo City General Hospital Sapporo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshihisa","family":"Anzai","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine Hokkaido University Sapporo 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