{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T15:43:14Z","timestamp":1789486994445,"version":"build-2803163510"},"reference-count":17,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T00:00:00Z","timestamp":1782777600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T00:00:00Z","timestamp":1782777600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Acute pericarditis is an uncommon complication of thermal atrial fibrillation (AF) ablation, whereas milder pericardial inflammatory symptoms, typically pleuritic or positional chest pain, are more common and negatively affect post\u2010procedural recovery. Pulsed field ablation (PFA), a non\u2010thermal modality with tissue\u2010selective properties, may reduce collateral pericardial injury. We compared post\u2010procedural pericardial inflammatory symptoms and recovery after AF ablation using PFA vs. radiofrequency ablation (RFA).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This single\u2010center observational study with prospective data collection included 150 patients undergoing catheter ablation for paroxysmal or persistent AF using focal PFA (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200975) or RFA (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200975). Patients were identified from the procedural workflow during the study period. Post\u2010procedural pericardial inflammatory symptoms, chest pain severity (5\u2010point scale), anti\u2010inflammatory therapy use, length of hospital stay, and biomarkers of inflammation (CRP) and myocardial injury (hs\u2010TnT) were assessed during hospitalization and structured post\u2010discharge follow\u2010up.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Baseline characteristics were similar between groups. Post\u2010procedural chest pain occurred more frequently after RFA than PFA (32% vs. 5.3%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), despite a significantly greater proportion of patients in the PFA group receiving lesion sets beyond pulmonary vein isolation (94.7% vs. 73.3%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Anti\u2010inflammatory therapy was prescribed more frequently after RFA (20% vs. 2.7%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001), and hospital length of stay was longer [2 (1\u20132) vs. 1(1\u20131) days,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.03). Procedure duration was shorter with PFA (86\u2009\u00b1\u200936 vs. 122\u2009\u00b1\u200955\u2009min,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Median hs\u2010TnT levels were higher after PFA [1288 (865\u20132137) vs. 1001 (652\u20131368] ng\/L,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.01), whereas CRP levels were similar [10.4 (4.9\u201323.3) vs. 10.5 (6.9\u201327.3) mg\/L;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.38].\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>PFA was associated with fewer post\u2010procedural pericardial inflammatory symptoms, reduced need for anti\u2010inflammatory therapy, and faster recovery compared with RFA. These findings suggest reduced pericardial irritation and improved patient\u2010centered recovery after AF ablation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jce.70424","type":"journal-article","created":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T19:54:58Z","timestamp":1782849298000},"page":"1930-1938","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Pulsed Field Ablation Is Associated With Fewer Post\u2010Procedural Pericardial Inflammatory Symptoms Compared With Radiofrequency Ablation"],"prefix":"10.1111","volume":"37","author":[{"given":"Dor","family":"Yadin","sequence":"first","affiliation":[{"name":"Cardiac Electrophysiology Section, Division of Cardiovascular Medicine Shamir Medical Center Be'er Yaakov Israel"},{"name":"Gray Faculty of Medical and Health Sciences Tel Aviv University Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Barkagan","sequence":"additional","affiliation":[{"name":"Cardiac Electrophysiology Section, Division of Cardiovascular Medicine Shamir Medical Center Be'er Yaakov Israel"},{"name":"Gray Faculty of Medical and Health Sciences Tel Aviv University Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maxime","family":"Zabern","sequence":"additional","affiliation":[{"name":"Cardiac Electrophysiology Section, Division of Cardiovascular Medicine Shamir Medical Center Be'er Yaakov Israel"},{"name":"Gray Faculty of Medical and Health Sciences Tel Aviv University Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sivan","family":"Hay","sequence":"additional","affiliation":[{"name":"Cardiac Electrophysiology Section, Division of Cardiovascular Medicine Shamir Medical Center Be'er Yaakov Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anat","family":"Milman","sequence":"additional","affiliation":[{"name":"Cardiac Electrophysiology Section, Division of Cardiovascular Medicine Shamir Medical Center Be'er Yaakov Israel"},{"name":"Gray Faculty of Medical and Health Sciences Tel Aviv University Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8199-2288","authenticated-orcid":false,"given":"Elad","family":"Anter","sequence":"additional","affiliation":[{"name":"Cardiac Electrophysiology Section, Division of Cardiovascular Medicine Shamir Medical Center Be'er Yaakov Israel"},{"name":"Gray Faculty of Medical and Health Sciences Tel Aviv University Tel Aviv 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