{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T20:29:15Z","timestamp":1783542555573,"version":"3.55.0"},"reference-count":23,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T00:00:00Z","timestamp":1783468800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T00:00:00Z","timestamp":1783468800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100007771","name":"\u015al\u0105ski Uniwersytet Medyczny","doi-asserted-by":"publisher","award":["BNW\u20101\u20101022\u2010N\/4\/K"],"award-info":[{"award-number":["BNW\u20101\u20101022\u2010N\/4\/K"]}],"id":[{"id":"10.13039\/100007771","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Long\u2010term mortality after transvenous lead extraction (TLE) remains substantial despite high procedural success. However, simple tools for estimating long\u2010term prognosis after successful TLE are lacking.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Results<\/jats:title>\n                    <jats:p>\n                      This retrospective multicenter study included 3368 consecutive patients undergoing TLE between 2006 and 2020 with complete 5\u2010year follow\u2010up. Patients were assigned in a 1:1 ratio to derivation and validation cohorts (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20091684 each). Independent predictors of mortality were identified using multivariable Cox proportional hazards analysis and incorporated into a point\u2010based risk score, the List of Independent Factors for Estimated 5\u2010Year Survival (LIFE\u20105S).\n                    <\/jats:p>\n                    <jats:p>\n                      During follow\u2010up, cumulative 5\u2010year mortality was 32.2%. Independent predictors included male sex, older age, permanent atrial fibrillation, advanced heart failure (NYHA class III\/IV), type 2 diabetes, renal dysfunction, reduced left ventricular ejection fraction, pocket infection, lead\u2010related infective endocarditis, and the presence of cardiac resynchronization therapy. Each 1\u2010point increase in the LIFE\u20105S score was associated with higher mortality risk (HR 1.36, 95% CI 1.33\u20131.39;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). The model demonstrated good discrimination (AUC 0.786 in the derivation cohort and 0.785 in the validation cohort) and good calibration across score strata. To facilitate clinical application, an online calculator based on the LIFE\u20105S model is available (\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"https:\/\/usuwanieelektrod.pl\/life5scalculator\">https:\/\/usuwanieelektrod.pl\/life5scalculator<\/jats:ext-link>\n                      ).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The LIFE\u20105S score provides a simple bedside tool for long\u2010term prognostic stratification after TLE. This model may support clinical decision\u2010making, patient counseling, and planning of individualized follow\u2010up strategies after TLE.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jce.70427","type":"journal-article","created":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T19:54:23Z","timestamp":1783540463000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Development and Validation of the LIFE\u20105S Score for Predicting 5\u2010Year Mortality After Transvenous Lead Extraction"],"prefix":"10.1111","author":[{"given":"Wojciech","family":"Jache\u0107","sequence":"first","affiliation":[{"name":"2nd Department of Cardiology Faculty of Medical Sciences in Zabrze, Medical University of Silesia Katowice Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u0141ukasz","family":"Tu\u0142ecki","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery The Pope John Paul II Province Hospital Zamo\u015b\u0107 Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2441-3876","authenticated-orcid":false,"given":"Dorota","family":"Nowosielecka","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery The Pope John Paul II Province Hospital Zamo\u015b\u0107 Poland"},{"name":"Faculty of Health Sciences, Academy of Zamo\u015b\u0107 Zamo\u015b\u0107 Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3990-1028","authenticated-orcid":false,"given":"Andrzej","family":"Kutarski","sequence":"additional","affiliation":[{"name":"2nd Department of Cardiology Faculty of Medical Sciences in Zabrze, Medical University of Silesia Katowice 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