{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T21:15:26Z","timestamp":1783545326048,"version":"3.55.0"},"reference-count":26,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T00:00:00Z","timestamp":1783468800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T00:00:00Z","timestamp":1783468800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Pre\u2010 and post\u2010procedural imaging in left atrial appendage occlusion (LAAO) adds to patient inconvenience and risks and may not materially influence outcomes. A more focused approach involving only peri\u2010procedural imaging may suffice.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Results<\/jats:title>\n                    <jats:p>\n                      Data from patients who had LAAO at our centre between 2009 and 2024 were examined. Those with pre\u2010 and post\u2010procedure imaging studies were excluded. Efficacy outcomes including procedural success and periprocedural complication were recorded. Long\u2010term outcomes comprising cerebrovascular events, major bleeding, cardiovascular and all\u2010cause death were retrieved through review of regional and national digital health records. 247 patients met the analysis criteria. The median CHA\n                      <jats:sub>2<\/jats:sub>\n                      DS\n                      <jats:sub>2<\/jats:sub>\n                      \u2010VASc and HAS\u2010BLED scores were 4 [interquartile range (IQR) 3\u20135)] and 3 (IQR 3\u20134) respectively. Successful closure of the left atrial appendage was achieved in 245 (99.2%) patients. Periprocedural death and complications occurred in 0.4% and 2.4% of patients respectively. Follow\u2010up was obtained for 1155 patient\u2010years (median follow\u2010up time 6.8 years). Clinical stroke occurred in 6.9% of patients (1.55 per 100 patient\u2010years)\u2014a 67% reduction compared to that expected from the CHA\n                      <jats:sub>2<\/jats:sub>\n                      DS\n                      <jats:sub>2<\/jats:sub>\n                      \u2010VASc score. 11.4% of patients suffered from major bleeding (2.56 per 100 patient\u2010years)\u2014a 55% reduction compared to that expected from the HAS\u2010BLED score. 40.8% (8.65 per 100 patient\u2010years) of patients died during follow\u2010up. Patients suffering from cerebrovascular events had higher CHA\n                      <jats:sub>2<\/jats:sub>\n                      DS\n                      <jats:sub>2<\/jats:sub>\n                      \u2010VASc (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.048) and HAS\u2010BLED scores (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.045).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>A minimalistic approach in LAAO using only periprocedural imaging guidance is feasible and safe, with an excellent success rate and a resultant reduction in cerebrovascular events in long\u2010term.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jce.70433","type":"journal-article","created":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T20:35:13Z","timestamp":1783542913000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Long\u2010Term Outcomes of Minimalist Left Atrial Appendage Occlusion Guided Only by Periprocedural Imaging"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9326-2648","authenticated-orcid":false,"given":"Siu\u2010Fung","family":"Wong","sequence":"first","affiliation":[{"name":"Department of Cardiology, Sussex Cardiac Centre University Hospitals Sussex  Brighton UK"},{"name":"Division of Cardiology, Department of Medicine and Geriatrics United Christian Hospital  Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Broyd","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Sussex Cardiac Centre University Hospitals Sussex  Brighton UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cara","family":"Hanley","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Sussex Cardiac Centre University Hospitals Sussex  Brighton UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-8703-851X","authenticated-orcid":false,"given":"Timothy","family":"Bagnall","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Sussex Cardiac Centre University Hospitals Sussex  Brighton UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Abouelasaad","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Sussex Cardiac Centre University Hospitals Sussex  Brighton UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Cockburn","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Sussex Cardiac Centre University Hospitals 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