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It focuses on recent reports on the evaluation and management of <jats:styled-content style=\"fixed-case\">OH<\/jats:styled-content> and provides practical advice for clinicians on how to screen, diagnose, and treat patients using behavioral, nonpharmacologic, and pharmacologic strategies. The authors also provide a stepwise approach on how to apply new findings to successfully control <jats:styled-content style=\"fixed-case\">OH<\/jats:styled-content> and reduce the risk of syncope and falls in these patients. Treatment of <jats:styled-content style=\"fixed-case\">OH<\/jats:styled-content> is also discussed in special situations such as in hypertensive and hospitalized patients. It should be noted, however, that research in this area is mostly limited to studies in small numbers of patients. 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