{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T21:23:36Z","timestamp":1778621016312,"version":"3.51.4"},"reference-count":27,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,4,16]],"date-time":"2014-04-16T00:00:00Z","timestamp":1397606400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"National Heart, Lung, and Blood Institute of the National Institutes of Health","award":["NO1-HC-35130"],"award-info":[{"award-number":["NO1-HC-35130"]}]},{"name":"National Heart, Lung, and Blood Institute of the National Institutes of Health","award":["HHSN268201100036C"],"award-info":[{"award-number":["HHSN268201100036C"]}]},{"name":"Pfizer, Inc."}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Clinical Hypertension"],"published-print":{"date-parts":[[2014,5]]},"abstract":"<jats:p>Few randomized trials have compared visit\u2010to\u2010visit variability (<jats:styled-content style=\"fixed-case\">VVV<\/jats:styled-content>) of systolic blood pressure (<jats:styled-content style=\"fixed-case\">SBP<\/jats:styled-content>) across drug classes. The authors compared <jats:styled-content style=\"fixed-case\">VVV<\/jats:styled-content> of <jats:styled-content style=\"fixed-case\">SBP<\/jats:styled-content> among 24,004 participants randomized to chlorthalidone, amlodipine, or lisinopril in the Antihypertensive and Lipid\u2010Lowering Treatment to Prevent Heart Attack Trial (<jats:styled-content style=\"fixed-case\">ALLHAT<\/jats:styled-content>). <jats:styled-content style=\"fixed-case\">VVV<\/jats:styled-content> of <jats:styled-content style=\"fixed-case\">SBP<\/jats:styled-content> was calculated across 5 to 7 visits occurring 6 to 28\u00a0months following randomization. The standard deviation (<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>) of <jats:styled-content style=\"fixed-case\">SBP<\/jats:styled-content> was 10.6 (<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>=5.0), 10.5 (<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>=4.9), and 12.2 (<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>=5.8) for participants randomized to chlorthalidone, amlodipine, and lisinopril, respectively. After multivariable adjustment including mean <jats:styled-content style=\"fixed-case\">SBP<\/jats:styled-content> across visits and compared with participants randomized to chlorthalidone, participants randomized to amlodipine had a 0.36 (standard error [<jats:styled-content style=\"fixed-case\">SE<\/jats:styled-content>]: 0.07) lower <jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content> of <jats:styled-content style=\"fixed-case\">SBP<\/jats:styled-content> and participants randomized to lisinopril had a 0.77 (<jats:styled-content style=\"fixed-case\">SE<\/jats:styled-content>=0.08) higher <jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content> of <jats:styled-content style=\"fixed-case\">SBP<\/jats:styled-content>. Results were consistent using other <jats:styled-content style=\"fixed-case\">VVV<\/jats:styled-content> of <jats:styled-content style=\"fixed-case\">SBP<\/jats:styled-content> metrics. These data suggest chlorthalidone and amlodipine are associated with lower <jats:styled-content style=\"fixed-case\">VVV<\/jats:styled-content> of <jats:styled-content style=\"fixed-case\">SBP<\/jats:styled-content> than lisinopril.<\/jats:p>","DOI":"10.1111\/jch.12290","type":"journal-article","created":{"date-parts":[[2014,4,16]],"date-time":"2014-04-16T15:22:43Z","timestamp":1397661763000},"page":"323-330","source":"Crossref","is-referenced-by-count":58,"title":["Effect of Chlorthalidone, Amlodipine, and Lisinopril on Visit\u2010to\u2010Visit Variability of Blood Pressure: Results From the Antihypertensive and Lipid\u2010Lowering Treatment to Prevent Heart Attack Trial"],"prefix":"10.1111","volume":"16","author":[{"given":"Paul","family":"Muntner","sequence":"first","affiliation":[{"name":"Department of Epidemiology University of Alabama at Birmingham Birmingham AL"},{"name":"Department of Medicine University of Alabama at Birmingham Birmingham AL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emily B.","family":"Levitan","sequence":"additional","affiliation":[{"name":"Department of Epidemiology University of Alabama at Birmingham Birmingham AL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amy I.","family":"Lynch","sequence":"additional","affiliation":[{"name":"Department of Epidemiology University of Alabama at Birmingham Birmingham AL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lara M.","family":"Simpson","sequence":"additional","affiliation":[{"name":"Division of Biostatistics School of Public Health The University of Texas Houston TX"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey","family":"Whittle","sequence":"additional","affiliation":[{"name":"Department of Medicine Medical College of Wisconsin Milwaukee WI"},{"name":"Primary Care Division Clement J. Zablocki VA Medical Center Milwaukee WI"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barry R.","family":"Davis","sequence":"additional","affiliation":[{"name":"Division of Biostatistics School of Public Health The University of Texas Houston TX"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John B.","family":"Kostis","sequence":"additional","affiliation":[{"name":"Department of Medicine Rutgers \u2013 Robert Wood Johnson Medical School New Brunswick NJ"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul K.","family":"Whelton","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Tulane University New Orleans LA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suzanne","family":"Oparil","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Alabama at Birmingham Birmingham AL"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,4,16]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)60308-X"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.110.162255"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.112.193094"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.108.120154"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-6175.2006.05781.x"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)60235-8"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0b013e328364ca4c"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0895-7061(96)00037-4"},{"key":"e_1_2_9_10_1","first-page":"573","article-title":"A multiple comparisons procedure for comparing several treatments with a control","volume":"60","author":"Dunnett CW","year":"1955","journal-title":"J Am Stat Assoc."},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.283.15.1967"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.288.23.2981"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/jhh.2013.19"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0b013e32834cf213"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-150-9-200905050-00006"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/mpr.329"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.4067"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(10)70066-1"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0b013e32835339ac"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)60309-1"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.112.194340"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/hr.2011.135"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005344-200109000-00011"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.hco.0000240587.14463.58"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/FJC.0b013e31803104e5"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.0000152701.97426.5f"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra060433"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/hr.2013.58"}],"container-title":["The Journal of Clinical Hypertension"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjch.12290","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjch.12290","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jch.12290","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T06:56:01Z","timestamp":1695538561000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jch.12290"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,4,16]]},"references-count":27,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2014,5]]}},"alternative-id":["10.1111\/jch.12290"],"URL":"https:\/\/doi.org\/10.1111\/jch.12290","archive":["Portico"],"relation":{},"ISSN":["1524-6175","1751-7176"],"issn-type":[{"value":"1524-6175","type":"print"},{"value":"1751-7176","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,4,16]]}}}