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The association of <jats:styled-content style=\"fixed-case\">AASI<\/jats:styled-content> with <jats:styled-content style=\"fixed-case\">magnetic resonance imaging (MRI)<\/jats:styled-content> markers of cerebral small vessel disease in 143 patients with lacunar stroke was investigated. We performed 24\u2010hour ambulatory blood pressure monitoring and scored the presence of lacunes, white matter hyperintensities, perivascular spaces, and cerebral microbleeds on brain <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>. In logistic regression analyses, <jats:styled-content style=\"fixed-case\">AASI<\/jats:styled-content> was associated with white matter hyperintensities, but, after adjustment for age and sex, this association lost significance. <jats:styled-content style=\"fixed-case\">AASI<\/jats:styled-content> was not associated with lacunes, microbleeds, or perivascular spaces. Systolic and diastolic 24\u2010hour blood pressure values were associated with lacunes, perivascular spaces, and microbleeds independent of age and sex. Despite its significance and growing interest as a possible prognostic and therapeutic target in (micro)vascular diseases, <jats:styled-content style=\"fixed-case\">AASI<\/jats:styled-content> seems to have no added value over standard 24\u2010hour blood pressure in cerebral small vessel disease.<\/jats:p>","DOI":"10.1111\/jch.12504","type":"journal-article","created":{"date-parts":[[2015,2,16]],"date-time":"2015-02-16T15:29:16Z","timestamp":1424100556000},"page":"352-356","source":"Crossref","is-referenced-by-count":4,"title":["Ambulatory Arterial Stiffness Index Is Not Associated With Magnetic Resonance Imaging Markers of Cerebral Small Vessel Disease in Lacunar Stroke Patients"],"prefix":"10.1111","volume":"17","author":[{"given":"Pim","family":"Klarenbeek","sequence":"first","affiliation":[{"name":"Department of Neurology Maastricht University Medical Centre Maastricht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert J.","family":"van 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