{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T12:38:26Z","timestamp":1780403906374,"version":"3.54.1"},"reference-count":30,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2015,5,20]],"date-time":"2015-05-20T00:00:00Z","timestamp":1432080000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Clinical Hypertension"],"published-print":{"date-parts":[[2015,9]]},"abstract":"<jats:p>Blood pressure (BP) in patients with sickle cell disease (SCD) has been reported to be lower than in persons in the general population. Data on arterial stiffness, which is an important risk factor for the progression of BP, are inconclusive for this patient population. Forty\u2010five adult patients with SCD and 40 controls matched for sex, age, and body mass index were studied. Brachial systolic BP (SBP) and diastolic BP (DBP) were significantly lower in the patient group (SBP 115.1\u00b113.8 mm Hg vs 121.9\u00b111.3 mm Hg and DBP 68.5\u00b18.0 mm Hg vs 80.6\u00b19.1 mm Hg, <jats:italic>P<\/jats:italic>&lt;.05, respectively). Augmentation index (AIx), however, was significantly higher in SCD patients compared with healthy controls (24.9\u00b19.6 for patients vs 12.4\u00b110.8 for controls, <jats:italic>P<\/jats:italic>&lt;.001), while carotid femoral pulse wave velocity was comparable between the two groups. The study shows that mechanisms other than arterial elasticity are involved in the low BP phenotype of patients with SCD.<\/jats:p>","DOI":"10.1111\/jch.12572","type":"journal-article","created":{"date-parts":[[2015,5,20]],"date-time":"2015-05-20T08:32:38Z","timestamp":1432110758000},"page":"726-731","source":"Crossref","is-referenced-by-count":24,"title":["Arterial Stiffness and Peripheral and Central Blood Pressure in Patients With Sickle Cell Disease"],"prefix":"10.1111","volume":"17","author":[{"given":"Maria","family":"Pikilidou","sequence":"first","affiliation":[{"name":"Hypertension Excellence Center AHEPA University Hospital Thessaloniki Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Yavropoulou","sequence":"additional","affiliation":[{"name":"Division of Clinical and Molecular Endocrinology AHEPA University Hospital Thessaloniki Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Antoniou","sequence":"additional","affiliation":[{"name":"Hypertension Excellence Center AHEPA University Hospital Thessaloniki Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleftherios","family":"Papakonstantinou","sequence":"additional","affiliation":[{"name":"Hypertension Excellence Center AHEPA University Hospital Thessaloniki Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Despoina","family":"Pantelidou","sequence":"additional","affiliation":[{"name":"Division of Hematology and Thalassemia Unit 1st Department of Internal Medicine AHEPA University Hospital Thessaloniki Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Panagiota","family":"Chalkia","sequence":"additional","affiliation":[{"name":"Division of Hematology and Thalassemia Unit 1st Department of Internal Medicine AHEPA University Hospital Thessaloniki Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Nilsson","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences Lund University Malmo Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Yovos","sequence":"additional","affiliation":[{"name":"Division of Clinical and Molecular Endocrinology AHEPA University Hospital Thessaloniki Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pantelis","family":"Zebekakis","sequence":"additional","affiliation":[{"name":"Hypertension Excellence Center AHEPA University Hospital Thessaloniki Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,5,20]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)08273-9"},{"key":"e_1_2_9_3_1","unstructured":"VichinskyE.Overview of the clinical manifestations of sickle cell disease. 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