{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T19:04:56Z","timestamp":1758395096565},"reference-count":25,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2015,10,5]],"date-time":"2015-10-05T00:00:00Z","timestamp":1444003200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Clinical Hypertension"],"published-print":{"date-parts":[[2016,5]]},"abstract":"Beta\u2010trace protein (BTP<\/jats:styled-content>) has emerged as a novel biomarker of cardiovascular risk. In this study, the authors aimed to assess the relationship between BTP<\/jats:styled-content> levels and presence of atrial fibrillation in patients who had controlled hypertension (HTN<\/jats:styled-content>) and normal renal function. A total of 80 controlled HTN<\/jats:styled-content> patients with paroxysmal atrial fibrillation (PAF<\/jats:styled-content>) and 80 age\u2010 and sex\u2010matched controls with controlled HTN<\/jats:styled-content> were enrolled. Serum BTP<\/jats:styled-content> levels were measured by enzyme\u2010linked immunosorbent assay. BTP<\/jats:styled-content> levels were found to be significantly higher in patients with PAF<\/jats:styled-content> (P<\/jats:italic><.001). Other parameters including mean systolic and diastolic blood pressure values, serum creatinine levels, and glomerular filtration rate were similar between the two groups. Along with left atrial diameter (odds ratio, 1.504; P<\/jats:italic><.001), BTP<\/jats:styled-content> levels (odds ratio, 1.015; P<\/jats:italic><.001) were independently associated with the presence of PAF<\/jats:styled-content>. BTP<\/jats:styled-content> levels were increased in controlled HTN<\/jats:styled-content> patients with PAF<\/jats:styled-content> compared with controls, and this association was observed within normal renal functions as reflected by normal glomerular filtration rate.<\/jats:p>","DOI":"10.1111\/jch.12703","type":"journal-article","created":{"date-parts":[[2015,10,5]],"date-time":"2015-10-05T10:28:54Z","timestamp":1444040934000},"page":"439-443","source":"Crossref","is-referenced-by-count":5,"title":["Elevated Serum Beta\u2010Trace Protein Levels are Associated With the Presence of Atrial Fibrillation in Hypertension Patients"],"prefix":"10.1111","volume":"18","author":[{"given":"Muhammed U.","family":"Yalcin","sequence":"first","affiliation":[{"name":"Department of Cardiology Hakkari State Hospital Hakkari Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kadri M.","family":"Gurses","sequence":"additional","affiliation":[{"name":"Department of Cardiology Konya Training and Research Hospital Konya Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Duygu","family":"Kocyigit","sequence":"additional","affiliation":[{"name":"Department of Cardiology Hacettepe University Faculty of Medicine Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sacit A.","family":"Kesikli","sequence":"additional","affiliation":[{"name":"Basic Oncology Department Hacettepe University Cancer Institute Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lale","family":"Tokgozoglu","sequence":"additional","affiliation":[{"name":"Department of Cardiology Hacettepe University Faculty of Medicine Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dicle","family":"Guc","sequence":"additional","affiliation":[{"name":"Basic Oncology Department Hacettepe University Cancer Institute Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kudret","family":"Aytemir","sequence":"additional","affiliation":[{"name":"Department of Cardiology Hacettepe University Faculty of Medicine Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Necla","family":"Ozer","sequence":"additional","affiliation":[{"name":"Department of Cardiology Hacettepe University Faculty of Medicine Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,10,5]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000041"},{"key":"e_1_2_8_3_1","unstructured":"Welcome to the Chronic Conditions Data WarehouseWeb site.www.ccwdata.org. 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