{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T20:13:00Z","timestamp":1787170380560,"version":"build-2736575974"},"reference-count":30,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2015,12,28]],"date-time":"2015-12-28T00:00:00Z","timestamp":1451260800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["HHSN268201300025C"],"award-info":[{"award-number":["HHSN268201300025C"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["HHSN268201300026C"],"award-info":[{"award-number":["HHSN268201300026C"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["HHSN268201300027C"],"award-info":[{"award-number":["HHSN268201300027C"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["HHSN268201300028C"],"award-info":[{"award-number":["HHSN268201300028C"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["HHSN268201300029C"],"award-info":[{"award-number":["HHSN268201300029C"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["HHSN268200900041C"],"award-info":[{"award-number":["HHSN268200900041C"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["R01 HL104199"],"award-info":[{"award-number":["R01 HL104199"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["AG0005"],"award-info":[{"award-number":["AG0005"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Clinical Hypertension"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:p>\n                    The effect of dietary isoflavone intake on systolic blood pressure (\n                    <jats:styled-content style=\"fixed-case\">SBP<\/jats:styled-content>\n                    ) has not been studied in a large community\u2010based cohort inclusive of African Americans. The authors analyzed data from the year 20 examination of the Coronary Artery Risk Development in Young Adults (\n                    <jats:styled-content style=\"fixed-case\">CARDIA<\/jats:styled-content>\n                    ) study, including medical history, physical examination, and dietary intake surveys for 3142 participants. Multivariable linear regression models controlled for age, sex, body mass index, smoking, physical activity, and intakes of alcohol and total energy. Effect modification by race was tested. Overall, patients with hypertension had a lower daily intake of total dietary isoflavones (2.2\u00b15.2 mg\/d vs 4.1\u00b111.7 mg\/d;\n                    <jats:italic>P<\/jats:italic>\n                    &lt;.001). In fully adjusted models, the highest quartile of dietary isoflavone intake was associated with a 4.4 mm Hg lower\n                    <jats:styled-content style=\"fixed-case\">SBP<\/jats:styled-content>\n                    on average compared with\n                    <jats:styled-content style=\"fixed-case\">SBP<\/jats:styled-content>\n                    for the lowest quartile. The relationship between dietary isoflavone intake and\n                    <jats:styled-content style=\"fixed-case\">SBP<\/jats:styled-content>\n                    was more pronounced among African Americans compared with Caucasians (\n                    <jats:italic>P<\/jats:italic>\n                    for interaction &lt;.001). Greater dietary intake of isoflavones was independently associated with a lower\n                    <jats:styled-content style=\"fixed-case\">SBP<\/jats:styled-content>\n                    .\n                  <\/jats:p>","DOI":"10.1111\/jch.12760","type":"journal-article","created":{"date-parts":[[2015,12,28]],"date-time":"2015-12-28T04:02:55Z","timestamp":1451275375000},"page":"778-783","source":"Crossref","is-referenced-by-count":22,"title":["Dietary Total Isoflavone Intake Is Associated With Lower Systolic Blood Pressure: The Coronary Artery Risk Development in Young Adults (\n                    <scp>CARDIA<\/scp>\n                    ) Study"],"prefix":"10.1111","volume":"18","author":[{"given":"Safiya I.","family":"Richardson","sequence":"first","affiliation":[{"name":"Department of Medicine Hofstra North Shore\u2010LIJ School of Medicine Manhasset NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lyn M.","family":"Steffen","sequence":"additional","affiliation":[{"name":"Division of Epidemiology and Community Health University of Minnesota Minneapolis MN"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katrina","family":"Swett","sequence":"additional","affiliation":[{"name":"Division of Public Health Sciences Wake Forest School of Medicine Winston\u2010Salem NC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Che","family":"Smith","sequence":"additional","affiliation":[{"name":"Division of Public Health Sciences Wake Forest School of Medicine Winston\u2010Salem NC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lora","family":"Burke","sequence":"additional","affiliation":[{"name":"University of Pittsburgh School of Nursing Pittsburgh PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xia","family":"Zhou","sequence":"additional","affiliation":[{"name":"Division of Epidemiology and Community Health University of Minnesota Minneapolis MN"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James M.","family":"Shikany","sequence":"additional","affiliation":[{"name":"Division of Preventive Medicine University of Alabama at Birmingham Birmingham AL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0860-9008","authenticated-orcid":false,"given":"Carlos J.","family":"Rodriguez","sequence":"additional","affiliation":[{"name":"Division of Public Health Sciences Wake Forest School of Medicine Winston\u2010Salem NC"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,12,28]]},"reference":[{"key":"e_1_2_10_2_1","first-page":"19","article-title":"Control of hypertension among adults\u2013\u2013National Health and Nutrition Examination Survey, United States, 2005\u20102008","volume":"61","author":"Yoon PW","year":"2012","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amepre.2010.02.016"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0b013e31820a55f5"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200101043440101"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-143-1-200507050-00004"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.167.10.1060"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/132.7.1900"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0b013e32833c6edb"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.numecd.2010.09.006"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.83.4.1465"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000158136.76824.04"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2010.1843"},{"key":"e_1_2_10_14_1","first-page":"15","article-title":"A study of the reliability and comparative validity of the cardia dietary history","volume":"4","author":"Liu K","year":"1993","journal-title":"Ethn Dis"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8223(21)01299-2"},{"key":"e_1_2_10_16_1","unstructured":"BhagwatS HaytowitzD HoldenJ.USDA Database for the Isoflavone Content of Selected Foods(Release 2.0).U.S. Department of Agriculture.2008.http:\/\/www.ars.usda.gov\/nutrientdata\/isoflav. 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