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The authors searched MEDLINE In\u2010Process &amp; Other Non\u2010Indexed Citations, Embase, and Cochrane Central Register of Controlled Trials. Prospective adult cohort studies with surgically treated PA that reported resolution of hypertension without the aid of medications were included. Among 2620 abstracts identified by the search, 25 studies in the systematic review with data on 1685 patients were investigated. The pooled proportion of normotension following adrenalectomy was 52% (95% confidence interval, 0.44\u20130.60). Meta\u2010regression demonstrated a significant negative association between length of follow\u2010up and proportion of normotension, with normotension dropping by 6.7% per year of follow\u2010up (coefficient \u22120.006; 95% confidence interval, \u22120.01 to 0.002). Overall, approximately half of the patients experienced hypertension resolution, although this outcome may not be durable in all patients.<\/jats:p>","DOI":"10.1111\/jch.12916","type":"journal-article","created":{"date-parts":[[2016,10,19]],"date-time":"2016-10-19T11:18:56Z","timestamp":1476875936000},"page":"1205-1212","source":"Crossref","is-referenced-by-count":46,"title":["Proportion of Patients With Hypertension Resolution Following Adrenalectomy for Primary Aldosteronism: A Systematic Review and Meta\u2010Analysis"],"prefix":"10.1111","volume":"18","author":[{"given":"Jamie L.","family":"Benham","sequence":"first","affiliation":[{"name":"Department of Medicine University of Calgary Calgary AB Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maysoon","family":"Eldoma","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Calgary Calgary AB Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bushra","family":"Khokhar","sequence":"additional","affiliation":[{"name":"Department of Community Health Sciences University of Calgary Calgary AB Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Derek J.","family":"Roberts","sequence":"additional","affiliation":[{"name":"Department of Surgery and Community Health Sciences University of Calgary Calgary AB Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doreen M.","family":"Rabi","sequence":"additional","affiliation":[{"name":"Department of Medicine, Community Health and Cardiac Sciences University of Calgary Calgary AB Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory A.","family":"Kline","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Calgary Calgary AB Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,10,19]]},"reference":[{"key":"e_1_2_10_2_1","first-page":"3","article-title":"Presidential address. 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