{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:11:54Z","timestamp":1790813514910,"version":"4.1.0"},"reference-count":35,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2017,9,17]],"date-time":"2017-09-17T00:00:00Z","timestamp":1505606400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["HHSN268201300046C"],"award-info":[{"award-number":["HHSN268201300046C"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["HHSN268201300047C"],"award-info":[{"award-number":["HHSN268201300047C"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["HHSN268201300048C"],"award-info":[{"award-number":["HHSN268201300048C"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["HHSN268201300049C"],"award-info":[{"award-number":["HHSN268201300049C"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["HHSN268201300050C"],"award-info":[{"award-number":["HHSN268201300050C"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006545","name":"National Institute on Minority Health and Health Disparities","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006545","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["K24\u2010HL125704"],"award-info":[{"award-number":["K24\u2010HL125704"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Clinical Hypertension"],"published-print":{"date-parts":[[2017,11]]},"abstract":"It is unclear whether black patients with chronic kidney disease (CKD<\/jats:styled-content>) vs those without CKD<\/jats:styled-content> who take antihypertensive medication have an increased risk for apparent treatment\u2010resistant hypertension (aTRH<\/jats:styled-content>). The authors analyzed 1741 Jackson Heart Study participants without aTRH<\/jats:styled-content> taking antihypertensive medication at baseline. aTRH<\/jats:styled-content> was defined as uncontrolled blood pressure while taking three antihypertensive medication classes or taking four or more antihypertensive medication classes, regardless of blood pressure level. CKD<\/jats:styled-content> was defined as an albumin to creatinine ratio \u226530\u00a0mg\/g or estimated glomerular filtration rate <60\u00a0mL<\/jats:styled-content>\/min\/1.73\u00a0m2<\/jats:sup>. Over 8\u00a0years, 20.1% of participants without CKD<\/jats:styled-content> and 30.5% with CKD<\/jats:styled-content> developed aTRH<\/jats:styled-content>. The multivariable\u2010adjusted hazard ratio for aTRH<\/jats:styled-content> comparing participants with CKD<\/jats:styled-content> vs those without CKD<\/jats:styled-content> was 1.45 (95% CI,<\/jats:styled-content> 1.12\u20131.86). Participants with an albumin to creatinine ratio<\/jats:styled-content> \u226530 vs <30\u00a0mg\/g (hazard ratio,<\/jats:styled-content> 1.44; 95% CI,<\/jats:styled-content> 1.04\u20132.00) and estimated glomerular filtration rate<\/jats:styled-content> of 45 to 59\u00a0mL<\/jats:styled-content>\/min\/1.73\u00a0m2<\/jats:sup> and <45 vs \u226560mL<\/jats:styled-content>\/min\/1.73\u00a0m2<\/jats:sup> (hazard ratio,<\/jats:styled-content> 1.60 [95% CI<\/jats:styled-content>, 1.16\u20132.20] and 2.05 [95% CI<\/jats:styled-content>, 1.28\u20133.26], respectively) were more likely to develop aTRH<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/jch.13065","type":"journal-article","created":{"date-parts":[[2017,9,18]],"date-time":"2017-09-18T14:18:28Z","timestamp":1505744308000},"page":"1117-1124","source":"Crossref","is-referenced-by-count":19,"title":["Chronic kidney disease and incident apparent treatment\u2010resistant hypertension among blacks: Data from the Jackson Heart Study"],"prefix":"10.1111","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6409-3611","authenticated-orcid":false,"given":"Rikki M.","family":"Tanner","sequence":"first","affiliation":[{"name":"Department of Epidemiology University of Alabama at Birmingham Birmingham AL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daichi","family":"Shimbo","sequence":"additional","affiliation":[{"name":"Department of Medicine Columbia University Medical Center New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marguerite R.","family":"Irvin","sequence":"additional","affiliation":[{"name":"Department of Epidemiology University of Alabama at Birmingham Birmingham AL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanya M.","family":"Spruill","sequence":"additional","affiliation":[{"name":"Department of Population Health New York University School of Medicine New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samantha G.","family":"Bromfield","sequence":"additional","affiliation":[{"name":"Department of Epidemiology University of Alabama at Birmingham Birmingham AL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samantha R.","family":"Seals","sequence":"additional","affiliation":[{"name":"Center of Biostatistics and Bioinformatics University of Mississippi Medical Center Jackson MS USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bessie A.","family":"Young","sequence":"additional","affiliation":[{"name":"Kidney Research Institute University of Washington Seattle WA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Muntner","sequence":"additional","affiliation":[{"name":"Department of Epidemiology University of Alabama at Birmingham Birmingham AL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,9,17]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.108.189141"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2009.09.014"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.166.17.1884"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.161.9.1207"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.115.06487"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.00550113"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.3109\/10641969609088965"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ki.5000177"},{"key":"e_1_2_9_10_1","first-page":"1029","article-title":"Influence of albuminuria and glomerular filtration rate on blood pressure response to antihypertensive drug therapy","volume":"3","author":"Flack JM","year":"2007","journal-title":"Vasc Health Risk Manag"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.030189"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.114.03850"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9629(15)40495-1"},{"issue":"6","key":"e_1_2_9_14_1","first-page":"S6\u20104\u201017","article-title":"Toward resolution of cardiovascular health disparities in African Americans: design and methods of the Jackson Heart Study","volume":"4","author":"Taylor HA .","year":"2005","journal-title":"Ethn Dis."},{"issue":"6","key":"e_1_2_9_15_1","first-page":"S6","article-title":"Recruiting African\u2010American research participation in the Jackson Heart Study: methods, response rates, and sample description","volume":"4","author":"Fuqua SR","year":"2005","journal-title":"Ethn Dis."},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAJ.0000000000000446"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-150-9-200905050-00006"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.107.100081"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.115.06904"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.0000107251.49515.c2"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2009.04.029"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(92)92624-O"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-148-7-200804010-00006"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.068064"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2013.11.016"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2005111200"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2010101085"},{"key":"e_1_2_9_28_1","unstructured":"USRDS.2015 United States Renal Data System annual data report: epidemiology of kidney disease in the United States.Bethesda MD:National Institutes of Health National Institute of Diabetes and Digestive and Kidney Diseases;2015."},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAJ.0000000000000308"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcna.2009.02.001"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.162.14.1636"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-142-5-200503010-00009"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0910975"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1001286"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2012.12.061"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehs368"}],"container-title":["The Journal of Clinical Hypertension"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjch.13065","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jch.13065","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T08:41:11Z","timestamp":1695544871000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jch.13065"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9,17]]},"references-count":35,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["10.1111\/jch.13065"],"URL":"https:\/\/doi.org\/10.1111\/jch.13065","archive":["Portico"],"relation":{},"ISSN":["1524-6175","1751-7176"],"issn-type":[{"value":"1524-6175","type":"print"},{"value":"1751-7176","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,9,17]]}}}