{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T00:05:05Z","timestamp":1781136305695,"version":"3.54.1"},"reference-count":36,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,2,16]],"date-time":"2018-02-16T00:00:00Z","timestamp":1518739200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Clinical Hypertension"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:p>Detection of renal artery stenosis (<jats:styled-content style=\"fixed-case\">RAS<\/jats:styled-content>) using Doppler is difficult to evaluate, particularly under conditions such as bilateral <jats:styled-content style=\"fixed-case\">RAS<\/jats:styled-content> or difficultly accessible renal arteries (<jats:styled-content style=\"fixed-case\">RA<\/jats:styled-content>). The objective of the present study was to assess the utility of splenic arterial compared to renal flow as an additional parameter in the Doppler evaluation of <jats:styled-content style=\"fixed-case\">RAS<\/jats:styled-content>. The difference between the resistive indices (<jats:styled-content style=\"fixed-case\">RI<\/jats:styled-content>) determined in renal and splenic parenchymal arteries (\u0394RI<jats:sub>K\u2212S<\/jats:sub>) was evaluated in 181 hypertensive subjects without any evidence of <jats:styled-content style=\"fixed-case\">RAS<\/jats:styled-content>. Subsequently 47 <jats:styled-content style=\"fixed-case\">RA<\/jats:styled-content> in 24 patients with suspected <jats:styled-content style=\"fixed-case\">RAS<\/jats:styled-content> were angiographically assessed. A \u0394RI<jats:sub>K\u2212S<\/jats:sub> of 0.055 (median) was determined in the population without any evidence of <jats:styled-content style=\"fixed-case\">RAS<\/jats:styled-content> similar to <jats:styled-content style=\"fixed-case\">RA<\/jats:styled-content> with angiographically excluded stenosis (\u0394RI<jats:sub>K\u2212S<\/jats:sub> 0.068). In contrast, in angiographic proven <jats:styled-content style=\"fixed-case\">RAS<\/jats:styled-content>, \u0394RI<jats:sub>K\u2212S<\/jats:sub> was significantly lower (\u22120.050; <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.005). The assessment of the \u0394RI<jats:sub>K\u2212S<\/jats:sub>, proved to be an easily feasible parameter, which improves the diagnostic accuracy in the detection of <jats:styled-content style=\"fixed-case\">RAS<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/jch.13212","type":"journal-article","created":{"date-parts":[[2018,2,16]],"date-time":"2018-02-16T05:26:44Z","timestamp":1518758804000},"page":"582-588","source":"Crossref","is-referenced-by-count":12,"title":["Difference between renal and splenic resistive index as a novel criterion in Doppler evaluation of renal artery stenosis"],"prefix":"10.1111","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4300-5293","authenticated-orcid":false,"given":"Clemens","family":"Grupp","sequence":"first","affiliation":[{"name":"Department of Nephrology &amp; Rheumatology Georg\u2010August\u2010University G\u00f6ttingen  G\u00f6ttingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Koziolek","sequence":"additional","affiliation":[{"name":"Department of Nephrology &amp; Rheumatology Georg\u2010August\u2010University G\u00f6ttingen  G\u00f6ttingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"Wallbach","sequence":"additional","affiliation":[{"name":"Department of Nephrology &amp; Rheumatology Georg\u2010August\u2010University G\u00f6ttingen  G\u00f6ttingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kerstin","family":"Hoxhold","sequence":"additional","affiliation":[{"name":"Department of Nephrology &amp; Rheumatology Georg\u2010August\u2010University G\u00f6ttingen  G\u00f6ttingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerhard A.","family":"M\u00fcller","sequence":"additional","affiliation":[{"name":"Department of Nephrology &amp; Rheumatology Georg\u2010August\u2010University G\u00f6ttingen  G\u00f6ttingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carsten","family":"Bramlage","sequence":"additional","affiliation":[{"name":"Department of Nephrology &amp; Rheumatology Georg\u2010August\u2010University G\u00f6ttingen  G\u00f6ttingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,2,16]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-150-12-200906160-00119"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.10491015"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0905368"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1310753"},{"key":"e_1_2_7_6_1","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1111\/jch.12341","article-title":"Proper patient selection yields significant and sustained reduction in systolic blood pressure following renal artery stenting in patients with uncontrolled hypertension: long\u2010term results from the HERCULES trial","volume":"16","author":"Chrysant GS","year":"2014","journal-title":"J Clin Hypertens (Greenwich)"},{"key":"e_1_2_7_7_1","article-title":"The effect of revascularization in patients with anatomically significant atherosclerotic renovascular disease presenting with high\u2010risk clinical features","author":"Vassallo D","year":"2017","journal-title":"Nephrol Dial Transplant"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.116.08124"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1269442"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/sdi.12140"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2017.04.013"},{"key":"e_1_2_7_12_1","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1111\/jch.12344","article-title":"Renal artery stenting in patients with uncontrolled hypertension: should we? 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