{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T04:05:56Z","timestamp":1790395556244,"version":"4.1.0"},"reference-count":50,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2018,3,22]],"date-time":"2018-03-22T00:00:00Z","timestamp":1521676800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Hypertension"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:p>Women with fibroids have a notably high hypertension risk. However, adjusted data regarding other cardiovascular disease (<jats:styled-content style=\"fixed-case\">CVD<\/jats:styled-content>) risk factors are scarce. In this cross\u2010sectional study, <jats:styled-content style=\"fixed-case\">CVD<\/jats:styled-content> risk factors, hemodynamic parameters, and asymptomatic organ damage were analyzed between women with uterine fibroids and controls in a multi\u2010ethnic population. In total, 104 women with self\u2010reported fibroids and 624 controls were included. Women with fibroids had significantly higher odds to have hypertension (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 3.4; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 2.2\u20105.2), diabetes (1.7; 1.0\u20102.9), and hypercholesterolemia (1.8; 1.1\u20103.2). After adjustment for confounders, only the odds ratio for hypertension was significant (1.8; 1.1\u20103.1). Asymptomatic organ damage occurred significantly more often in women with fibroids (66.7%; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 55.8%\u201077.6% vs 42.9%; 38.0\u201047.8 in controls), especially in the younger age group (respectively 48.5%; 31.1%\u201065.9% vs 22.1%; 17.0\u201027.2). In this study, women with fibroids had a remarkably high hypertension risk compared to controls, with more asymptomatic organ damage, in particular young women.<\/jats:p>","DOI":"10.1111\/jch.13253","type":"journal-article","created":{"date-parts":[[2018,3,23]],"date-time":"2018-03-23T04:59:57Z","timestamp":1521781197000},"page":"718-726","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":63,"title":["The risk of hypertension and cardiovascular disease in women with uterine fibroids"],"prefix":"10.1111","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8238-2342","authenticated-orcid":false,"given":"Yentl C.","family":"Haan","sequence":"first","affiliation":[{"name":"Department of Vascular Medicine Academic Medical Center  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederieke S.","family":"Diemer","sequence":"additional","affiliation":[{"name":"Department of Vascular Medicine Academic Medical Center  Amsterdam the Netherlands"},{"name":"Department of Cardiology Academic Hospital Paramaribo  Paramaribo Suriname"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Van Der Woude","sequence":"additional","affiliation":[{"name":"Department of Vascular Medicine Academic Medical Center  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gert A.","family":"Van Montfrans","sequence":"additional","affiliation":[{"name":"Department of Vascular Medicine Academic Medical Center  Amsterdam the Netherlands"},{"name":"Department of Internal Medicine Academic Medical Center  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Glenn P.","family":"Oehlers","sequence":"additional","affiliation":[{"name":"Department of Cardiology Academic Hospital Paramaribo  Paramaribo Suriname"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7434-0038","authenticated-orcid":false,"given":"Lizzy M.","family":"Brewster","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Academic Medical Center  Amsterdam the Netherlands"},{"name":"Department of Public Health Anton de Kom University of Suriname  Paramaribo Suriname"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,3,22]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"e38","article-title":"Heart disease and stroke statistics\u20102016 update: a report from the American Heart Association","volume":"133","author":"Writing Group Members","year":"2016","journal-title":"Circulation"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2015.01.027"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.968792"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajh\/hpu183"},{"key":"e_1_2_6_6_1","first-page":"359","article-title":"Fibroids and hypertension. 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