{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T06:57:01Z","timestamp":1790146621723,"version":"4.0.1"},"reference-count":27,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2018,9,14]],"date-time":"2018-09-14T00:00:00Z","timestamp":1536883200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Hypertension"],"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:p>\n                    Accumulation of fat in renal sinus and hilum is associated with hypertension development. We evaluated the relationship between perirenal fat and hypertension in a population of morbidly obese patients and the potential variations after sleeve\u2010gastrectomy. Two hundred and eighty\u2010four morbidly obese patients were included in the study, and 126 underwent sleeve\u2010gastrectomy. At baseline and 10\u201012\u00a0months after surgery, we evaluated anthropometric parameters, blood pressure, glycometabolic, and lipidic assessment, and performed an ultrasonographic evaluation of visceral fat area and perirenal fat thickness. The perirenal fat thickness in hypertensive obese was higher than in nonhypertensive (13.6\u00a0\u00b1\u00a04.8 vs 11.6\u00a0\u00b1\u00a04.1,\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0=\u00a00.001). It showed a significant direct correlation with age, waist circumference, BMI, systolic blood pressure (SBP), insulinemia, HOMA\u2010IR, glycated hemoglobin, and creatinine. The independent predictors (\n                    <jats:italic>R<\/jats:italic>\n                    <jats:sup>2<\/jats:sup>\n                    \u00a0=\u00a00.129) of SBP were perirenal fat thickness (\n                    <jats:italic>\u03b2<\/jats:italic>\n                    \u00a0=\u00a00.160,\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0=\u00a00.022) and age (\n                    <jats:italic>\u03b2<\/jats:italic>\n                    \u00a0=\u00a00.175,\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0=\u00a00.011). After surgery, perirenal fat thickness significantly decreased (from 13\u00a0\u00b1\u00a04 to 9\u00a0\u00b1\u00a04\u00a0mm,\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0&lt;0.001). In the 89 hypertensive obese patients who underwent sleeve\u2010gastrectomy, we observed a significant decrease in antihypertensive medications needed. Sixteen patients suspended therapy. The perirenal fat thickness in obese patients could be a valuable tool to define the risk of developing hypertension, providing the clinician with an additional parameter to define those who need a more aggressive treatment and could benefit most from bariatric surgery.\n                  <\/jats:p>","DOI":"10.1111\/jch.13370","type":"journal-article","created":{"date-parts":[[2018,9,16]],"date-time":"2018-09-16T04:27:15Z","timestamp":1537072035000},"page":"1430-1437","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":68,"title":["Morbid obesity and hypertension: The role of perirenal fat"],"prefix":"10.1111","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1326-7535","authenticated-orcid":false,"given":"Maria Anastasia","family":"Ricci","sequence":"first","affiliation":[{"name":"Internal Medicine, Department of Medicine S. Maria della Misericordia Hospital Perugia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Scavizzi","sequence":"additional","affiliation":[{"name":"Internal Medicine, Department of Medicine S. Maria della Misericordia Hospital Perugia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Ministrini","sequence":"additional","affiliation":[{"name":"Internal Medicine, Department of Medicine S. Maria della Misericordia Hospital Perugia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"De Vuono","sequence":"additional","affiliation":[{"name":"Internal Medicine, Department of Medicine S. Maria della Misericordia Hospital Perugia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giacomo","family":"Pucci","sequence":"additional","affiliation":[{"name":"Internal Medicine Unit Santa Maria Hospital Terni Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Graziana","family":"Lupattelli","sequence":"additional","affiliation":[{"name":"Internal Medicine, Department of Medicine S. Maria della Misericordia Hospital Perugia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,9,14]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2008.08.022"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0091-7435(87)90087-9"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004872-199412000-00018"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJNRD.S39739"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-134-1-200101020-00007"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.110.157370"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12872-015-0101-6"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.111.175315"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrcardio.2016.162"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1503\/cjs.036111"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc09-9033"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.44.794"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2014.07.005"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1291\/hypres.30.229"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/jch.12049"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.116.08791"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-144-1-200601030-00006"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(14)70065-8"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.2337\/diab.37.12.1595"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfm037"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0175561"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/hr.2010.9"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2013.3654"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.f5934"},{"issue":"248","key":"e_1_2_6_26_1","first-page":"e5","article-title":"Weight and type 2 diabetes after bariatric surgery: systematic review and meta\u2010analysis","volume":"122","author":"Buchwald H","year":"2009","journal-title":"Am J Med"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1200225"},{"key":"e_1_2_6_28_1","first-page":"3","article-title":"The Metabolic effects of laparoscopic sleeve gastrectomy: a review","volume":"2","author":"Noah J","year":"2013","journal-title":"J Minim Invasive Surg Sci"}],"container-title":["The Journal of Clinical Hypertension"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjch.13370","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jch.13370","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,17]],"date-time":"2023-09-17T03:12:18Z","timestamp":1694920338000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jch.13370"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9,14]]},"references-count":27,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2018,10]]}},"alternative-id":["10.1111\/jch.13370"],"URL":"https:\/\/doi.org\/10.1111\/jch.13370","archive":["Portico"],"relation":{},"ISSN":["1524-6175","1751-7176"],"issn-type":[{"value":"1524-6175","type":"print"},{"value":"1751-7176","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,9,14]]},"assertion":[{"value":"2018-05-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-07-23","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-09-14","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}