{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T13:49:59Z","timestamp":1775051399990,"version":"3.50.1"},"reference-count":31,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2018,10,13]],"date-time":"2018-10-13T00:00:00Z","timestamp":1539388800000},"content-version":"vor","delay-in-days":12,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100008903","name":"Ministry of Health and Welfare","doi-asserted-by":"publisher","award":["HC16C2285"],"award-info":[{"award-number":["HC16C2285"]}],"id":[{"id":"10.13039\/100008903","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Hypertension"],"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:p>The presence of abdominal obesity and lack of physical activity are both risk factors for the development of hypertension. The aim of this study was to analyze the risk of developing hypertension according to baseline waist circumference (WC). In total, 16\u00a0312\u00a0476 non\u2010hypertensive participants who were covered by the National Health Insurance Service (NHIS) from 2009 to 2012 in Korea were included in the study. The participants were divided into six groups according to the level of baseline WC with a 5\u2010cm interval starting from 80\u00a0cm in men and 75\u00a0cm in women. The risk for the future development of hypertension was assessed in 2015 using the claims data on the diagnosis of hypertension and prescription of anti\u2010hypertensive medications. Approximately 7.8% of the participants developed hypertension over a median follow\u2010up of 5.48\u00a0years. The proportion of participants who developed hypertension significantly increased from 4.2% in the WC level 1% to 17.5% in the WC level 6. After adjusting for confounding factors, level 6 of the baseline WC had a higher hazard ratio (HR) for the development of hypertension among the 6 levels of baseline with level 3 as the reference (1736; 95% confidence interval [95% CI]: 1.72\u20101.753). The participants with abdominal obesity had a significantly higher HR than those without abdominal obesity regardless of whether they engage in high\u2010 or moderate\u2010intensity physical intensity (1.741; 95% CI: 1.718\u20101.764). WC had a linear association with the development of hypertension based on this large nationwide population\u2010based cohort study, which was not influenced by physical activity.<\/jats:p>","DOI":"10.1111\/jch.13389","type":"journal-article","created":{"date-parts":[[2018,10,13]],"date-time":"2018-10-13T11:02:01Z","timestamp":1539428521000},"page":"1417-1426","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Association between abdominal obesity and increased risk for the development of hypertension regardless of physical activity: A nationwide population\u2010based study"],"prefix":"10.1111","volume":"20","author":[{"given":"Eun\u2010Jung","family":"Rhee","sequence":"first","affiliation":[{"name":"Division of Endocrinology and Metabolism, Department of Internal Medicine Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jung\u2010Hwan","family":"Cho","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Metabolism, Department of Internal Medicine Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyemi","family":"Kwon","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Metabolism, Department of Internal Medicine Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Se\u2010Eun","family":"Park","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Metabolism, Department of Internal Medicine Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin\u2010Hyung","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Biomedicine &amp; Health Sciences Catholic University College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyung\u2010Do","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Biomedicine &amp; Health Sciences Catholic University College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong\u2010Gyu","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Biomedicine &amp; Health Sciences Catholic University College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9514-2401","authenticated-orcid":false,"given":"Hye Soon","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Family Medicine, Asan Medical Center University of Ulsan College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang\u2010Hyun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Family Medicine Korea University Hospital, College of Medicine, Korea University Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soon\u2010Jib","family":"Yoo","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Metabolism, Department of Internal Medicine Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea Bucheon Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1082-7592","authenticated-orcid":false,"given":"Won\u2010Young","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Metabolism, Department of Internal Medicine Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea Bucheon Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Taskforce Team of the Obesity Fact Sheet of the Korean Society for the Study of Obesity","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,10,13]]},"reference":[{"key":"e_1_2_8_2_1","unstructured":"Available athttps:\/\/www.oecd.org\/health\/health-systems\/Obesity-Update-2017.pdf. 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