{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T00:49:59Z","timestamp":1771548599910,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,3,13]],"date-time":"2019-03-13T00:00:00Z","timestamp":1552435200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Hypertension"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:p>The correlations between organ damage and hourly ambulatory blood pressure (BP) have not been established. The patients were 1464 participants of the Japan Morning Surge\u2010Home Blood Pressure (J\u2010HOP) study participants who underwent ambulatory BP monitoring. The hourly systolic BP (SBP) at x\u00a0o'clock was defined as the average of SBP values measured at times x\u00a0\u2212\u00a030\u00a0minutes, x, and x\u00a0+\u00a030\u00a0minutes. The mean age was 64.8\u00a0\u00b1\u00a011.6\u00a0years. The percentage of male participants was 47.8%. The left ventricular mass index (LVMI) was significantly associated with SBP at 6\u00a0o'clock (<jats:italic>r<\/jats:italic>\u00a0=\u00a00.166, <jats:italic>P\u00a0&lt;\u00a0<\/jats:italic>0.001). The carotid intima\u2010media thickness was significantly associated with SBP at 5\u00a0o'clock (<jats:italic>r<\/jats:italic>\u00a0=\u00a00.196, <jats:italic>P\u00a0&lt;\u00a0<\/jats:italic>0.001). After adjustment for age, sex, smoking, hyperlipidemia, diabetes mellitus, antihypertensive drug use, clinic SBP, and 24\u2010hour ambulatory SBP, the correlations of the LVMI and hourly SBP at 6\u00a0o'clock remained significant (beta coefficient\u00a0=\u00a00.125, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.01). In conclusion, morning ambulatory systolic BP especially at 5 and 6\u00a0o'clock was independently associated with organ damage.<\/jats:p>","DOI":"10.1111\/jch.13498","type":"journal-article","created":{"date-parts":[[2019,3,14]],"date-time":"2019-03-14T05:20:27Z","timestamp":1552540827000},"page":"579-586","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Early morning\u2014Best time window of hourly 24\u2010hour ambulatory blood pressure in relation to hypertensive organ damage: The Japan Morning Surge\u2010Home Blood Pressure study"],"prefix":"10.1111","volume":"21","author":[{"given":"Sirisawat","family":"Wanthong","sequence":"first","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Medicine Jichi Medical University School of Medicine Tochigi Japan"},{"name":"Department of Medicine, Faculty of Medicine, Siriraj Hospital Mahidol University Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoyuki","family":"Kabutoya","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Medicine Jichi Medical University School of Medicine Tochigi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7541-5751","authenticated-orcid":false,"given":"Satoshi","family":"Hoshide","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Medicine Jichi Medical University School of Medicine Tochigi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peera","family":"Buranakitjaroen","sequence":"additional","affiliation":[{"name":"Department of Medicine, Faculty of Medicine, Siriraj Hospital Mahidol University Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8251-4480","authenticated-orcid":false,"given":"Kazuomi","family":"Kario","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Medicine Jichi Medical University School of Medicine Tochigi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,3,13]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.19043"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/eht151"},{"key":"e_1_2_8_4_1","unstructured":"National Institute for Health and Care Excellence.Hypertension: Clinical management of primary hypertension in adults (Clinical guideline 127).http:\/\/guidance.nice.org.uk\/CG127"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/hr.2014.20"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0b013e3282f97854"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.107.100727"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/jch.13086"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1291\/hypres.29.581"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.113.01838"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11906-015-0537-1"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000056521.67546.AA"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.115.04800"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/jch.12707"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-7176.2008.07427.x"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/jch.12500"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-88-0020"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199302043280502"},{"key":"e_1_2_8_19_1","first-page":"579","volume-title":"Essential Manual on Perfect 24\u2010hour Blood Pressure Management from Morning to Nocturnal Hypertension: Up\u2010to\u2010Date for Anticipation Medicine","author":"Kario K","year":"2018"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2015.05.005"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1567-4231(09)70054-1"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-6175.2007.06299.x"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/jch.13140"}],"container-title":["The Journal of Clinical Hypertension"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjch.13498","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jch.13498","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jch.13498","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/am-pdf\/10.1111%2Fjch.13498","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jch.13498","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T10:06:39Z","timestamp":1694340399000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jch.13498"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3,13]]},"references-count":22,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2019,5]]}},"alternative-id":["10.1111\/jch.13498"],"URL":"https:\/\/doi.org\/10.1111\/jch.13498","archive":["Portico"],"relation":{},"ISSN":["1524-6175","1751-7176"],"issn-type":[{"value":"1524-6175","type":"print"},{"value":"1751-7176","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,3,13]]},"assertion":[{"value":"2018-09-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-12-14","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-03-13","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}