{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T07:52:38Z","timestamp":1794037958530,"version":"4.8.0"},"reference-count":42,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,3,7]],"date-time":"2019-03-07T00:00:00Z","timestamp":1551916800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Hypertension"],"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:p>Hypertensive disorders of pregnancy (HDP) are a major contributor to maternal and perinatal morbidity and mortality, especially in resource\u2010limited settings. Little is known about the magnitude of HDP in Africa. We conducted the first systematic review and meta\u2010analysis to summarize available data on the prevalence of HDP in Africa. We did a comprehensive literature search to identify review paper published from January 1, 1996, to September 30, 2017, and searched the reference list of retrieved review paper. We used a random\u2010effects model to estimate the overall and type\u2010specific prevalence of HDP in Africa. We included 82 studies published between 1997 and 2017 reporting data on a pooled sample of 854\u00a0304 women during pregnancy or puerperium. Most studies were hospital\u2010based, conducted in urban settings across 24 countries. In this population, the overall prevalence of HDP was 100.4\u2030 (95% CI: 81.4\u2010121.2). The prevalence was 49.8\u2030 (95% CI: 32.3\u201070.7) for gestational hypertension, 14.7\u2030 (95% CI: 11.6\u201018.2) for chronic hypertension, 9.2\u2030 (95% CI: 4.2\u201016.0) for superimposed preeclampsia, 44.0\u2030 (95% CI: 36.7\u201052.0) for preeclampsia, 22.1\u2030 (95% CI: 14.8\u201030.8) for severe preeclampsia, 14.7\u2030 (95% CI: 8.1\u201023.2) for eclampsia and 2.2\u2030 (95% CI: 1.2\u20103.4) for HELLP syndrome. Prevalence of HDP was significantly higher in Central and Western Africa; there was a consistent tendency of increasing HDP prevalence with income at the country level. In conclusion, the burden of HDP in Africa is high, with about one in 10 pregnancies affected. The higher rate of severe forms of HDP that are associated with significant maternal and perinatal mortality is a major concern in the region.<\/jats:p>","DOI":"10.1111\/jch.13514","type":"journal-article","created":{"date-parts":[[2019,3,8]],"date-time":"2019-03-08T01:19:48Z","timestamp":1552007988000},"page":"479-488","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":95,"title":["The burden of hypertensive disorders of pregnancy in Africa: A systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7722-9757","authenticated-orcid":false,"given":"Jean Jacques","family":"Noubiap","sequence":"first","affiliation":[{"name":"Department of Medicine Groote Schuur Hospital, University of Cape Town Cape Town South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8018-6279","authenticated-orcid":false,"given":"Jean Joel","family":"Bigna","sequence":"additional","affiliation":[{"name":"Faculty of Medicine University of Paris Sud XI Le Kremlin\u2010Bic\u00eatre France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrich Flore","family":"Nyaga","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and Specialties, Faculty of Medicine and Biomedical Sciences University of Yaound\u00e9 1 Yaound\u00e9 Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmadou M.","family":"Jingi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and Specialties, Faculty of Medicine and Biomedical Sciences University of Yaound\u00e9 1 Yaound\u00e9 Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnaud D.","family":"Kaze","sequence":"additional","affiliation":[{"name":"University of Maryland Medical Center Midtown Campus Baltimore Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jobert Richie","family":"Nansseu","sequence":"additional","affiliation":[{"name":"Department of Public Health, Faculty of Medicine and Biomedical Sciences University of Yaound\u00e9 1 Yaound\u00e9 Cameroon"},{"name":"Department for the Control of Disease, Epidemics and Pandemics Ministry of Public Health Yaound\u00e9 Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4722-9262","authenticated-orcid":false,"given":"Jo\u00ebl","family":"Fokom Domgue","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics Yaound\u00e9 University Teaching Hospital Yaound\u00e9 Cameroon"},{"name":"Department of Gynecologic Oncology and Reproductive Medicine The University of Texas MD Anderson Cancer Center Houston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,3,7]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)31679-8"},{"key":"e_1_2_8_3_1","volume-title":"A Global Brief on Hypertension: Silent Killer, Global Public Health Crisis. 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