{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:24:13Z","timestamp":1747185853534,"version":"3.40.5"},"reference-count":43,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2019,5,24]],"date-time":"2019-05-24T00:00:00Z","timestamp":1558656000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Hypertension"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Previous studies suggest an increased cancer risk in hypertension. Patients with hypertensive nephropathy have not been studied. A national registry study was performed to assess the presence and size of this association. Clinical data and cancer diagnoses for all patients with biopsy\u2010proven hypertensive nephropathy between 1985 and 2015 in Denmark were extracted from four national registries and compared with age\u2010 and sex\u2010adjusted national cancer rates. The risk of cancer was twice the background population. It was raised for renal cancer (odds ratio 10.4), myeloma (13.2), skin cancer (7.9), and other\/unspecified (1.8). No increase in incidence was seen until 1\u00a0year before renal biopsy and then rose rapidly. It was again normal 5\u00a0years after biopsy. Hypertensive nephropathy is associated with an increased risk of myeloma, skin, renal, and other cancers. Screening of patients with hypertensive nephropathy, in the presence of reduced renal function or significant proteinuria, may be indicated.<\/jats:p>","DOI":"10.1111\/jch.13565","type":"journal-article","created":{"date-parts":[[2019,5,25]],"date-time":"2019-05-25T06:41:16Z","timestamp":1558766476000},"page":"786-791","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Hypertensive nephropathy is associated with an increased risk of myeloma, skin, and renal cancer"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3715-3388","authenticated-orcid":false,"given":"James Goya","family":"Heaf","sequence":"first","affiliation":[{"name":"Department of Medicine Zealand University Hospital Roskilde Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alastair","family":"Hansen","sequence":"additional","affiliation":[{"name":"Institute of Clinical Medicine, Herlev Hospital University of Copenhagen Herlev Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gunnar Hellmund","family":"Laier","sequence":"additional","affiliation":[{"name":"Department of Production, Research and Innovation Region Zealand Sor\u00f8 Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,5,24]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19870401)59:7<1386::AID-CNCR2820590726>3.0.CO;2-B"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1081\/CNV-200055962"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00053150"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910630212"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19970601)79:11<2171::AID-CNCR15>3.0.CO;2-T"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a116178"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a009157"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200011023431804"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.306.6878.609"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a113105"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.03770412"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.critrevonc.2008.08.003"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2012.484"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrneph.2010.171"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40620-015-0234-9"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199601043340103"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2008060621"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61602-X"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-1755.2004.00832.x"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1177\/1403494810393562"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.3109\/02841861003782017"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1054\/bjoc.2001.2040"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2006.07.130"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1998.248"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/PPO.0b013e3181867628"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.20618"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clml.2015.06.003"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(10)70106-6"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(10)70260-6"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0b013e328344a7de"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.k4209"},{"key":"e_1_2_12_33_1","first-page":"115","article-title":"Epidemiologic aspects of renal cell cancer","volume":"27","author":"McLaughlin JK","year":"2000","journal-title":"Semin Oncol"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwm170"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.2174\/157488607780598296"},{"key":"e_1_2_12_36_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a009848"},{"key":"e_1_2_12_37_1","doi-asserted-by":"publisher","DOI":"10.3390\/toxins4110962"},{"key":"e_1_2_12_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2011.10507.x"},{"key":"e_1_2_12_39_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12882-018-0828-2"},{"key":"e_1_2_12_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(99)06154-1"},{"key":"e_1_2_12_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2008.08.135"},{"key":"e_1_2_12_42_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.30.9.868"},{"key":"e_1_2_12_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semnephrol.2010.09.011"},{"key":"e_1_2_12_44_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1008830431939"}],"container-title":["The Journal of Clinical Hypertension"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jch.13565","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jch.13565","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jch.13565","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T15:19:25Z","timestamp":1694359165000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jch.13565"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,24]]},"references-count":43,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["10.1111\/jch.13565"],"URL":"https:\/\/doi.org\/10.1111\/jch.13565","archive":["Portico"],"relation":{},"ISSN":["1524-6175","1751-7176"],"issn-type":[{"type":"print","value":"1524-6175"},{"type":"electronic","value":"1751-7176"}],"subject":[],"published":{"date-parts":[[2019,5,24]]},"assertion":[{"value":"2018-12-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-04-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-05-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}