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Different etiologies have been suggested for nonlobar CMB, which have a stronger connection to hypertension (HT) than do lobar CMB. This study aimed to investigate the prevalence of CMB and the association between nonlobar\/lobar CMB and different blood pressure (BP) and HT treatment conditions in a longitudinal, population\u2010based cohort of the Good Aging in Sk\u00e5ne (G\u00c5S) study. White matter hyperintensities (WMH), CMB, atrophies, and infarctions were identified with brain 3T MRI, and BP parameters were examined in 344 randomly selected subjects between 70 and 87\u00a0years old. CMB were observed in 26% of the whole cohort, increasing from 19% of subjects in their 70s to 30% of those over 80\u00a0years of age. Of these subjects, 38% had multiple CMB, and 59% had a lobar localization. CMB were associated with severe confluent WMH (odds ratio\u00a0=\u00a07.02; 2.16\u201018.84). Increasing age, being male, and having HT, impaired cognition, or a history of angina pectoris were associated with CMB. Both lobar and nonlobar CMB were associated with HT. Nonlobar CMB were particularly associated with increased BP, pulse pressure, controlled HT, and uncontrolled HT. After controlling for sex and HT, age was no longer a risk factor for CMB <jats:italic>In conclusion<\/jats:italic>, sex and HT are the major risk factors for CMB, especially nonlobar CMB, which suggests stricter implementation of recommended guidelines for HT treatment in the elderly.<\/jats:p>","DOI":"10.1111\/jch.13606","type":"journal-article","created":{"date-parts":[[2019,7,5]],"date-time":"2019-07-05T11:09:07Z","timestamp":1562324947000},"page":"1099-1107","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["Association between cerebral microbleeds and hypertension in the Swedish general population \u201cGood Aging in Sk\u00e5ne\u201d study"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7153-5414","authenticated-orcid":false,"given":"S\u00f6lve","family":"Elmst\u00e5hl","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences in Malm\u00f6, Division of Geriatric Medicine, Sk\u00e5ne University Hospital Lund University Malm\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katarina","family":"Ellstr\u00f6m","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences in Malm\u00f6, Division of Geriatric Medicine, Sk\u00e5ne University Hospital Lund University Malm\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arkadiusz","family":"Siennicki\u2010Lantz","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences in Malm\u00f6, Division of Geriatric Medicine, Sk\u00e5ne University Hospital Lund University Malm\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kasim","family":"Abul\u2010Kasim","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences Lund, Division of Diagnostic Radiology, Sk\u00e5ne University Hospital Lund University Malm\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,7,5]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(09)70013-4"},{"key":"e_1_2_9_3_1","first-page":"637","article-title":"Histopathologic analysis of foci of signal loss on gradient\u2010echo T2*\u2010weighted MR images in patients with spontaneous intracerebral hemorrhage: evidence of microangiopathy\u2010related microbleeds","volume":"20","author":"Fazekas F","year":"1999","journal-title":"AJNR Am J 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