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Recent studies have demonstrated that body fat percentage (BF%) is associated with cardiometabolic risk factors. The aim of this study was to investigate the association between a change in BF% and body mass index (BMI) and the incidence of new\u2010onset hypertension in a normotensive Korean cohort. At baseline (2001\u20102002), 8848 participants aged 40\u201070\u00a0years were recruited for the study; follow\u2010up surveys were completed in the year 2012. A total of 3902 adults (1866 men and 2036 women) were included in the final analysis. These subjects were divided into quartile groups according to changes in BF% and were followed for 8.4\u00a0years to monitor for the development of hypertension. A Poisson regression model was used to evaluate the relative risk (RR) for hypertension according to BF% change quartile. Additionally, we also stratified participants into four groups according to BMI change levels and body fat change levels. Finally, we compared two factors, BF% change, and BMI change, to determine which is more predictive of incident hypertension. In an adjusted model, compared with the lowest BF% quartile group, the risk of new\u2010onset hypertension significantly increased with BF% change: Changes in risk were 0%\u20102.0% for quartile 3 subjects (RR: 1.32 [1.06\u20101.63]) and 2.0%\u20108.9% for quartile 4 participants (RR: 1.78 [1.43\u20102.19]). We also revealed that the RR for new\u2010onset hypertension was 1.81 (95% CI: 1.47\u20102.21) for quartile 4 group subjects, compared with subjects in quartile 1 (change in BMI \u22126.80 to \u22120.86% [kg\/m<jats:sup>2<\/jats:sup>]). Body fat gain and BMI increase were predictors of hypertension in this community\u2010based Korean cohort.<\/jats:p>","DOI":"10.1111\/jch.13723","type":"journal-article","created":{"date-parts":[[2019,10,29]],"date-time":"2019-10-29T16:14:22Z","timestamp":1572365662000},"page":"1849-1857","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Body fat change and 8\u2010year incidence of hypertension: Korean Genome and Epidemiology Study"],"prefix":"10.1111","volume":"21","author":[{"given":"Sung\u2010Bum","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Family Medicine Yonsei University College of Medicine, Gang-nam Severance Hospital Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A\u2010Ra","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Family Medicine Yonsei University College of Medicine, Gang-nam Severance Hospital Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu\u2010Jin","family":"Kwon","sequence":"additional","affiliation":[{"name":"Department of Medicine Graduate School of Yonsei University College of Medicine Seoul South Korea"},{"name":"Department of Family Medicine Yonsei University College of Medicine, Yong-in Severance Hospital Gyeonggi-do South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3411-0676","authenticated-orcid":false,"given":"Dong\u2010Hyuk","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Family Medicine Yonsei University College of Medicine, Yong-in Severance Hospital Gyeonggi-do South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,10,29]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)61766-8"},{"key":"e_1_2_9_3_1","volume-title":"A Global Brief on Hypertension: Silent Killer, Global Public Health Crisis: World Health Day 2013","author":"World Health Organization","year":"2013"},{"key":"e_1_2_9_4_1","unstructured":"Korean Statistical Information Service.Hypertension: \u226530 years by sex. 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