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The disagreement between central and peripheral BP has long been recognized. Some previous studies showed that noninvasive central BP may be better than the conventional brachial BP in association with target organ damages and long\u2010term cardiovascular outcomes. Recent studies further suggest that the central BP strategy for confirming a diagnosis of hypertension may be more cost\u2010effective than the conventional strategy, and guidance of hypertension management with central BP may result in less use of medications to achieve BP control. Despite the use of central BP being promising, more randomized controlled studies comparing central BP\u2010guided therapeutic strategies with conventional care for cardiovascular events reduction are required because noninvasive central and brachial BP measures are conveniently available. In this brief review, the rationale supporting the utility of central BP in clinical practice and relating challenges are summarized.<\/jats:p>","DOI":"10.1111\/jch.13758","type":"journal-article","created":{"date-parts":[[2019,12,16]],"date-time":"2019-12-16T10:16:06Z","timestamp":1576491366000},"page":"391-406","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":41,"title":["Central blood pressure for the management of hypertension: Is it a practical clinical tool in current practice?"],"prefix":"10.1111","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3885-6600","authenticated-orcid":false,"given":"Hao\u2010Min","family":"Cheng","sequence":"first","affiliation":[{"name":"Faculty of Medicine School of Medicine National Yang\u2010Ming University Taipei Taiwan"},{"name":"Center for Evidence\u2010Based Medicine Taipei Veterans General Hospital Taipei Taiwan"},{"name":"Institute of Public Health National 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