{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T21:40:38Z","timestamp":1782250838876,"version":"3.54.5"},"reference-count":22,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,3,10]],"date-time":"2021-03-10T00:00:00Z","timestamp":1615334400000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004319","name":"Pfizer","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004319","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Hypertension"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Increased heart rate is a predictor of cardiovascular disease, heart failure, and all\u2010cause mortality. In those with high heart rates, interventions for heart rate reduction have been associated with reductions in coronary events. Asia is a diverse continent, and the prevalences of hypertension and cardiovascular disease differ among its countries. The present analysis of AsiaBP@Home study data investigated differences among resting heart rates (RHRs) in 1443 hypertensive patients from three Asian regions: East Asia (<jats:italic>N<\/jats:italic>\u00a0=\u00a0595), Southeast Asia (<jats:italic>N<\/jats:italic>\u00a0=\u00a0680), and South Asia (<jats:italic>N<\/jats:italic>\u00a0=\u00a0168). This is the first study to investigate self\u2010measured RHR values in different Asian countries\/regions using the same validated home BP monitoring device (Omron HEM\u20107130\u2010AP\/HEM\u20107131\u2010E). Subjects in South Asia had higher RHR values compared with the other two regions, and the regional tendency found in RHR values was different from that found in BP values. Even after adjusting for age, sex, BMI, habitual alcohol consumption, current smoking habit, shift worker, hyperlipidemia, diabetes, chronic kidney disease, history of heart failure, and beta\u2010blocker use, both office and home RHR values in South Asia were the highest among Asia (mean values\u00a0\u00b1\u00a0SE of office: East Asia [E] 75.2\u00a0\u00b1\u00a01.5\u00a0bpm, Southeast Asia [Se] 76.7\u00a0\u00b1\u00a01.5\u00a0bpm, South Asia [S] 81.9\u00a0\u00b1\u00a01.4\u00a0bpm; home morning: [E] 69.0\u00a0\u00b1\u00a01.2\u00a0bpm, [Se] 72.9\u00a0\u00b1\u00a01.2\u00a0bpm, [S] 74.9\u00a0\u00b1\u00a01.1\u00a0bpm; home evening: [E] 74.6\u00a0\u00b1\u00a01.2\u00a0bpm, [Se] 78.3\u00a0\u00b1\u00a01.2\u00a0bpm, [S] 83.8\u00a0\u00b1\u00a01.1\u00a0bpm). Given what is known about the impact of RHR on heart disease, our findings suggest the possible benefit of regionally tailored clinical strategies for cardiovascular disease prevention.<\/jats:p>","DOI":"10.1111\/jch.14239","type":"journal-article","created":{"date-parts":[[2021,3,11]],"date-time":"2021-03-11T01:26:42Z","timestamp":1615426002000},"page":"606-613","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Regional differences in office and self\u2010measured home heart rates in Asian hypertensive patients: AsiaBP@Home study"],"prefix":"10.1111","volume":"23","author":[{"given":"Naoko","family":"Tomitani","sequence":"first","affiliation":[{"name":"Division of Cardiovascular Medicine Department of Medicine Jichi Medical University School of Medicine Tochigi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Hoshide","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine Department of Medicine Jichi Medical University School of Medicine Tochigi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peera","family":"Buranakitjaroen","sequence":"additional","affiliation":[{"name":"Division of Hypertension Department of Medicine Faculty of Medicine Siriraj Hospital Mahidol University Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yook Chin","family":"Chia","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences School of Healthcare and Medical Sciences Sunway University Bandar Sunway Malaysia"},{"name":"Department of Primary Care Medicine Faculty of Medicine University of Malaya Kuala Lumpur Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sungha","family":"Park","sequence":"additional","affiliation":[{"name":"Division of Cardiology Cardiovascular Hospital Yonsei Health System Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen\u2010Huan","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Medicine Faculty of Medicine National Yang\u2010Ming University Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Nailes","sequence":"additional","affiliation":[{"name":"University of the East Ramon Magsaysay Memorial Medical Center Inc Quezon City Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinho","family":"Shin","sequence":"additional","affiliation":[{"name":"Faculty of Cardiology Service Hanyang University Medical Center Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saulat","family":"Siddique","sequence":"additional","affiliation":[{"name":"Punjab Medical Center Lahore Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge","family":"Sison","sequence":"additional","affiliation":[{"name":"Department of Medicine Medical Center Manila Manila Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arieska Ann","family":"Soenarta","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Vascular Medicine University of Indonesia\u2010National Cardiovascular Center, Harapan Kita Jakarta Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guru Prasad","family":"Sogunuru","sequence":"additional","affiliation":[{"name":"MIOT International Hospital Chennai India"},{"name":"College of Medical Sciences Kathmandu University Bharatpur Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jam Chin","family":"Tay","sequence":"additional","affiliation":[{"name":"Department of General Medicine Tan Tock Seng Hospital Singapore City Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuda","family":"Turana","sequence":"additional","affiliation":[{"name":"Department of Neurology School of Medicine and Health Science Atma Jaya Catholic University of Indonesia Jakarta Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuqing","family":"Zhang","sequence":"additional","affiliation":[{"name":"Divisions of Hypertension and Heart Failure Fu Wai Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sirisawat","family":"Wanthong","sequence":"additional","affiliation":[{"name":"Division of Hypertension Department of Medicine Faculty of Medicine Siriraj Hospital Mahidol University Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noriko","family":"Matsushita","sequence":"additional","affiliation":[{"name":"Omron Healthcare Singapore, Pte. 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