{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T18:35:00Z","timestamp":1792521300165,"version":"4.5.0"},"reference-count":43,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,2,25]],"date-time":"2022-02-25T00:00:00Z","timestamp":1645747200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81703288"],"award-info":[{"award-number":["81703288"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Hypertension"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Carotid\u2010femoral pulse wave velocity (cfPWV) and brachial\u2010ankle pulse wave velocity (baPWV) act as two most frequently applied indicators to evaluate arterial stiffness. Limited studies have systematically compared the relationships between cfPWV\/baPWV and increased carotid intima\u2010media thickness (cIMT). This study aimed to investigate the associations of the two PWV indices with cIMT in a Chinese community\u2010based population. A total of 6026 Chinese participants from an atherosclerosis cohort were included in our analysis. Increased cIMT was defined as the maximum of cIMT\u00a0&gt;\u00a00.9\u00a0mm in end\u2010systolic period of carotid artery. Mean (SD) cfPWV and baPWV were 8.55\u00b11.83\u00a0 and 16.79\u00b13.35\u00a0m\/s, respectively. The prevalence of increased cIMT was 59.58%. In multivariable logistic regression, both PWVs were independently associated with increased cIMT after adjustment for various confounders (for 1\u00a0m\/s increase of cfPWV: OR\u00a0=\u00a01.07, 95% CI: 1.02\u20101.11; for 1\u00a0m\/s increase of baPWV: OR\u00a0=\u00a01.03, 95% CI: 1.00\u20101.05). The highest cfPWV and baPWV quartile groups had higher prevalence of increased cIMT when compared with the lowest quartile groups (for cfPWV: OR\u00a0=\u00a01.28, 95% CI: 1.06\u20101.55; for baPWV: OR\u00a0=\u00a01.23, 95% CI: 1.00\u20101.50). However, when both PWVs were added into multivariable model simultaneously, only cfPWV was associated with odds of increased cIMT. Subgroup analyses further showed cfPWV was more strongly associated with increased cIMT than baPWV in males, participants aged \u226565 years, and those with other cardiovascular risk factors. In conclusion, both cfPWV and baPWV are associated with increased cIMT in a Chinese community\u2010based population. Furthermore, cfPWV is more strongly correlated with increased cIMT compared to baPWV.<\/jats:p>","DOI":"10.1111\/jch.14448","type":"journal-article","created":{"date-parts":[[2022,2,25]],"date-time":"2022-02-25T22:31:29Z","timestamp":1645828289000},"page":"409-417","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Brachial\u2010ankle pulse wave velocity as a measurement for increased carotid intima\u2010media thickness: A comparison with carotid\u2010femoral pulse wave velocity in a Chinese community\u2010based cohort"],"prefix":"10.1111","volume":"24","author":[{"given":"Danmei","family":"He","sequence":"first","affiliation":[{"name":"Department of Cardiology Peking University First Hospital  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lan","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Cardiology Peking University First Hospital  Beijing 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