{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:09:02Z","timestamp":1787015342394,"version":"build-2736575974"},"reference-count":16,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Hypertension"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    This study assessed the efficacy and safety of sacubitril\/valsartan in 23 hemodialysis patients with hypertension (mean age 70 years; male 69.6%) after switching from azilsartan, an angiotensin receptor blocker. Both at baseline and 3 months after the start of sacubitril\/valsartan treatment, home blood pressure (BP), BP values during hemodialysis, and N\u2010terminal pro\u2010brain natriuretic peptide (NT\u2010proBNP) level were measured. The mean dosage of azilsartan was 30\u00a0\u00b1\u00a010\u00a0mg\/day at baseline and that of sacubitril\/valsartan after 3 months of treatment was 204\u00a0\u00b1\u00a064\u00a0mg\/day. After 3 months, significant reductions in mean morning home BP (155\u00a0\u00b1\u00a017\/80\u00a0\u00b1\u00a012 to 147\u00a0\u00b1\u00a016\/76\u00a0\u00b1\u00a011\u00a0mmHg), mean nighttime home systolic BP (153\u00a0\u00b1\u00a019 to 144\u00a0\u00b1\u00a016\u00a0mmHg), and median (IQRs) NT\u2010proBNP level [8124 (2620\u201313 394) to 6271 (1570\u20139591) pg\/mL] were observed (all\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0&lt;\u00a0.05), whereas BP values during hemodialysis did not change significantly. In hemodialysis patients, except for hypotension, sacubitril\/valsartan was generally well tolerated, effectively controlled out\u2010of\u2010office BP, and improved NT\u2010proBNP.\n                  <\/jats:p>","DOI":"10.1111\/jch.14635","type":"journal-article","created":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T05:39:44Z","timestamp":1675229984000},"page":"304-308","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Efficacy and safety of sacubitril\/valsartan after switching from azilsartan in hemodialysis patients with hypertension"],"prefix":"10.1111","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1932-7324","authenticated-orcid":false,"given":"Yoshio","family":"Iwashima","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Kansai Medical University Kori Hospital  Neyagawa Osaka Japan"},{"name":"Department of Nephrology and Hypertension Dokkyo Medical University  Mibu Tochigi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiromichi","family":"Fukushima","sequence":"additional","affiliation":[{"name":"Division of Internal Medicine Mooka Hospital  Mooka Tochigi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Horio","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Ishikiriseiki Hospital  Higashiosaka Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatemitsu","family":"Rai","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Hypertension Dokkyo Medical University  Mibu Tochigi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshihiko","family":"Ishimitsu","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Hypertension Dokkyo Medical University  Mibu Tochigi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,2]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrneph.2016.129"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2020.01.046"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/sdi.12369"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41440-022-00923-2"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/hr.2015.1"},{"issue":"1","key":"e_1_2_8_7_1","first-page":"S43","article-title":"Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. 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