{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T13:51:25Z","timestamp":1761745885568,"version":"3.40.5"},"reference-count":27,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2023,9,14]],"date-time":"2023-09-14T00:00:00Z","timestamp":1694649600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Hypertension"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Hypertensive crisis poses substantial cardiovascular morbidity and mortality. This study aimed to assess in\u2010hospital mortality, length of stay (LOS), and their predictors among patients with hypertensive crisis treated at public hospitals in Harari Regional State, Eastern Ethiopia. An institutional\u2010based retrospective cohort study was conducted from October 1 to 31, 2022. The medical records of 328 patients with hypertensive crisis treated at two public hospitals between September 1, 2017 and August 31, 2022 were reviewed. Cox proportional hazards regression and negative binomial regression were used to identify predictors of in\u2010hospital mortality and LOS, respectively. The in\u2010hospital mortality rate of patients with hypertensive crisis was 18.94 (95% confidence interval (CI): 12.08\u201329.70) per 1000 person\u2010day observation. The median (interquartile range) LOS of these patients was 10 (4\u2013120) hours. Age \u226565 years (adjusted hazard ratio (AHR): 3.30; 95% CI: 1.17\u2013 9.33); increment in initial systolic blood pressure (AHR: 1.040; 95% CI: 1.014\u20131.066); and having acute brain\u2010related damage (AHR: 4.02; 95% CI: 1.48\u201310.88) were predictors of in\u2010hospital mortality. Rural residence (adjusted incident\u2010rate ratio (IRR): 1.34; 95% CI: 1.03\u20131.75); having a history of medication discontinuation (adjusted IRR: 1.59; 95% CI: 1.16\u20132.18); comorbidity (adjusted IRR: 1.90; 95% CI: 1.49\u20132.43); acute brain\u2010related damage (adjusted IRR: 13.32; 95% CI: 9.22\u201319.24), acute cardiac\u2010related damage (adjusted IRR: 7.40; 95% CI: 4.90\u201311.16); and acute kidney injury (adjusted IRR: 7.64; 95% CI: 5.46\u201310.69) were predictors of LOS. Thus, it is necessary to develop strategies that allow early screening and follow\u2010up of patients at risk.<\/jats:p>","DOI":"10.1111\/jch.14728","type":"journal-article","created":{"date-parts":[[2023,9,14]],"date-time":"2023-09-14T18:15:19Z","timestamp":1694715319000},"page":"905-914","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["In\u2010hospital mortality and length of stay of patients with hypertensive crisis treated at public hospitals in Harari Regional State, Eastern Ethiopia"],"prefix":"10.1111","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8727-8950","authenticated-orcid":false,"given":"Natanim","family":"Degefu","sequence":"first","affiliation":[{"name":"Department of Pharmaceutics School of Pharmacy College of Health and Medical Sciences Haramaya University  Harar Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dumessa","family":"Edessa","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacy School of Pharmacy College of Health and Medical Sciences Haramaya University  Harar Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melaku","family":"Getachew","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine School of Medicine College of Health and Medical Sciences Haramaya University  Harar Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aboma","family":"Motuma","sequence":"additional","affiliation":[{"name":"School of Nursing and Midwifery College of Health and Medical Sciences Haramaya University  Harar Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lemma Demissie","family":"Regassa","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics School of Public Health College of Health and Medical Sciences Haramaya University  Harar Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,9,14]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40292\u2010018\u20100272\u20101"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.121.054602"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/circresaha.116.303603"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/413071"},{"key":"e_1_2_9_6_1","first-page":"399","volume-title":"Tintinalli's Emergency Medicine a Comprehensive Study Guide","author":"Baumann BM","year":"2020"},{"issue":"8","key":"e_1_2_9_7_1","first-page":"916","article-title":"Hypertensive crisis. 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