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The authors aim to investigate the association between BP\u2010derived hemodynamic parameters and PCI. Clinical data and BP recordings were collected from 80 patients with cerebral infarction, including 40 patients with PCI and 40 patients with non\u2010progressive cerebral infarction (NPCI). Hemodynamic parameters were calculated from the BP recordings of the first 7\u00a0days after admission, including systolic and diastolic BP, mean arterial pressure, and pulse pressure (PP), with the mean values of each group calculated and compared between daytime and nighttime, and between different days. Hemodynamic parameters and circadian BP rhythm patterns \u00a0were compared between PCI and NPCI groups using <jats:italic>t<\/jats:italic>\u2010test or non\u2010parametric equivalent for continuous variables, Chi\u2010squared test or Fisher's exact test for categorical variables, Cox proportional hazards regression analysis and binary logistic regression analysis for potential risk factors. In PCI and NPCI groups, significant decrease of daytime systolic BP appeared on the second and sixth days, respectively. Systolic BP and fibrinogen at admission, daytime systolic BP of the first day, nighttime systolic BP of the third day, PP, and the ratio of abnormal BP circadian rhythms were all higher in the PCI group. PCI and NPCI groups were significantly different in BP circadian rhythm pattern. PCI is associated with higher systolic BP, PP and more abnormal circadian rhythms of BP.<\/jats:p>","DOI":"10.1111\/jch.14759","type":"journal-article","created":{"date-parts":[[2024,1,9]],"date-time":"2024-01-09T05:08:23Z","timestamp":1704776903000},"page":"122-133","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Hemodynamic changes in progressive cerebral infarction: An observational study based on blood pressure monitoring"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3628-1364","authenticated-orcid":false,"given":"Ling","family":"Li","sequence":"first","affiliation":[{"name":"Department of Neurology Zhoushan Hospital Wenzhou Medical University  Zhoushan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bin","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Neurology People's Hospital of Quzhou  Quzhou 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