{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T16:50:26Z","timestamp":1790009426927,"version":"4.0.1"},"reference-count":39,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,7,22]],"date-time":"2024-07-22T00:00:00Z","timestamp":1721606400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Hypertension"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    It remained debates on metabolic\u2010related disorders in patients with primary aldosteronism (PA) and essential hypertension (EH). A systematic review and meta\u2010analysis was conducted to explore the prevalence of metabolic syndrome (MS) and the related indicators in PA and EH. PubMed, Embase, Web of Science and the Cochrane Central Register of Controlled Trials from their commencement to December 2023 were searched for eligible studies. The meta\u2010analysis was performed by Review Manager 5.3 and STATA 15.1 software. A total of 12 studies were included, revealing that there was no significant difference between PA and EH in the prevalence of MS (1.27[0.92, 1.76],\n                    <jats:italic>p\u00a0<\/jats:italic>\n                    =\u00a00.14) with higher heterogeneity (\n                    <jats:italic>I<\/jats:italic>\n                    <jats:sup>2<\/jats:sup>\n                    \u00a0=\u00a068%,\n                    <jats:italic>p\u00a0<\/jats:italic>\n                    =\u00a00.0002), while it became significant different (1.45[1.17, 1.81],\n                    <jats:italic>p\u00a0<\/jats:italic>\n                    =\u00a00.0008) and lower heterogeneity (\n                    <jats:italic>I<\/jats:italic>\n                    <jats:sup>2<\/jats:sup>\n                    \u00a0=\u00a026%,\n                    <jats:italic>p\u00a0<\/jats:italic>\n                    =\u00a00.19) in patients who were overweight or obese by subgroup analysis. Higher systolic blood pressure (2.99[0.67, 5.31],\n                    <jats:italic>p\u00a0<\/jats:italic>\n                    =\u00a00.01;\n                    <jats:italic>I<\/jats:italic>\n                    <jats:sup>2<\/jats:sup>\n                    \u00a0=\u00a043%,\n                    <jats:italic>p\u00a0<\/jats:italic>\n                    =\u00a00.06) and diastolic blood pressure (2.10[0.82, 3.38],\n                    <jats:italic>p\u00a0<\/jats:italic>\n                    =\u00a00.001;\n                    <jats:italic>I<\/jats:italic>\n                    <jats:sup>2<\/jats:sup>\n                    \u00a0=\u00a036%,\n                    <jats:italic>p\u00a0<\/jats:italic>\n                    =\u00a00.11) with lower heterogeneity, and lower triglyceride in PA group with higher heterogeneity (\u20100.23[\u20100.37, \u20100.09],\n                    <jats:italic>p\u00a0<\/jats:italic>\n                    =\u00a00.001;\n                    <jats:italic>I<\/jats:italic>\n                    <jats:sup>2<\/jats:sup>\n                    \u00a0=\u00a076%,\n                    <jats:italic>p\u00a0<\/jats:italic>\n                    &lt;\u00a00.0001) were observed. No significant difference was found in other indicators. This study showed a higher prevalence of MS in patients who were overweight or obese with PA. However, it was not the same in these patients who were in normal weight. More researches were needed to explore the relationship between PA and metabolism of glucose and lipid.\n                  <\/jats:p>","DOI":"10.1111\/jch.14873","type":"journal-article","created":{"date-parts":[[2024,7,22]],"date-time":"2024-07-22T08:28:15Z","timestamp":1721636895000},"page":"879-889","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["The prevalence of metabolic syndrome in primary aldosteronism and essential hypertension: A systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"26","author":[{"given":"Kaiwen","family":"Sun","sequence":"first","affiliation":[{"name":"Department of Cardiology First Affiliated Hospital of Dalian Medical University  Dalian Liaoning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenxu","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Cardiology First Affiliated Hospital of Dalian Medical University  Dalian Liaoning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minghui","family":"Gong","sequence":"additional","affiliation":[{"name":"Department of Cardiology First Affiliated Hospital of Dalian Medical University  Dalian Liaoning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Cardiology First Affiliated Hospital of Dalian Medical University  Dalian Liaoning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yinong","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Cardiology First Affiliated Hospital of Dalian Medical University  Dalian Liaoning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4973-7236","authenticated-orcid":false,"given":"Wei","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Cardiology First Affiliated Hospital of Dalian Medical University  Dalian Liaoning China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,7,22]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2020.02.052"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1210\/clinem\/dgac460"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11906-022-01176-7"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/MNH.0000000000000702"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2022.869980"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2022.884302"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(17)30319-4"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajh\/hpac079"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2022.870047"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12902-022-01135-y"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.3502"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23020786"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2009.06.005"},{"key":"e_1_2_13_15_1","unstructured":"Agency for Healthcare Research and Quality.AHRQ secure site methods article alerteEHC Scientific Resource Center EPCSRC.org. 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