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Participants were distributed into two groups: Non\u2010COVID\u201019 group (NCG: men <jats:italic>n<\/jats:italic> = 6 [30\u00a0\u00b1\u00a03years; 26\u00a0\u00b1\u00a01\u00a0kg\/m<jats:sup>2<\/jats:sup>] and women <jats:italic>n<\/jats:italic> = 5 [25\u00a0\u00b1\u00a01 years; 25\u00a0\u00b1\u00a01\u00a0kg\/m<jats:sup>2<\/jats:sup>]) and recovered from COVID\u201019 group (RCG: men <jats:italic>n<\/jats:italic> = 6 [29\u00a0\u00b1\u00a03 years; 25\u00a0\u00b1\u00a01\u00a0kg\/m<jats:sup>2<\/jats:sup>] and women <jats:italic>n<\/jats:italic> = 10 [32\u00a0\u00b1\u00a04 years; 22\u00a0\u00b1\u00a01\u00a0kg\/m<jats:sup>2<\/jats:sup>]), the RCG tested positive (RT\u2010PCR) 12 to 14 weeks before the protocol. Beat\u2010to\u2010beat finger blood pressure (BP) and heart rate (HR) were measured during a bolus of sodium nitroprusside (SNP) and phenylephrine (PHE), in a control condition and during cold pressor test (CPT) and moderate dynamic handgrip exercise (GRIP). Resting systolic BP was higher in the RCG (135\u00a0\u00b1\u00a014\u00a0mmHg vs. 122\u00a0\u00b1\u00a012\u00a0mmHg, <jats:italic>p<\/jats:italic> = 0.01). Both CPT and GRIP maneuvers increased HR and BP; the bolus of SNP diminished BP and evoked a reflex\u2010mediated increase in HR; PHE increased BP, resulting in a reflex\u2010mediated decrease in HR. Of note, cBRS for decrease or increase of BP did not differ between groups under the studied conditions: control (SNP, <jats:italic>p<\/jats:italic> = 0.39; PHE, <jats:italic>p<\/jats:italic> = 0.50); CPT (SNP, <jats:italic>p<\/jats:italic> = 0.09; PHE: <jats:italic>p<\/jats:italic> = 0.82); and GRIP (SNP, <jats:italic>p<\/jats:italic> = 0.35; PHE, <jats:italic>p<\/jats:italic> = 0.53). In conclusion, mild COVID\u201019 did not seem to impair cBRS in healthy young men and women 12\u201314 weeks after recovering from the infection.<\/jats:p>","DOI":"10.1111\/jch.70006","type":"journal-article","created":{"date-parts":[[2025,2,17]],"date-time":"2025-02-17T10:34:27Z","timestamp":1739788467000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Cardiac Baroreflex Is Preserved After the Recovery From COVID\u201019 Men and Women"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-2485-9698","authenticated-orcid":false,"given":"Roberto","family":"Souza","sequence":"first","affiliation":[{"name":"Laboratory of Exercise Science Department of Physiology and Pharmacology Fluminense Federal University  Niteroi Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beatriz","family":"Divino","sequence":"additional","affiliation":[{"name":"Laboratory of Exercise Science Department of Physiology and Pharmacology Fluminense Federal University  Niteroi Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4741-7343","authenticated-orcid":false,"given":"Helena N. M.","family":"Rocha","sequence":"additional","affiliation":[{"name":"Laboratory of Exercise Science Department of Physiology and Pharmacology Fluminense Federal University  Niteroi Brazil"},{"name":"Laboratory of Integrative Cardiometabology Department of Physiology and Pharmacology Fluminense Federal University  Niteroi Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6791-3910","authenticated-orcid":false,"given":"Jocemir R.","family":"Lugon","sequence":"additional","affiliation":[{"name":"Department of Medicine Medical School Fluminense Federal University  Niteroi Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1990-9834","authenticated-orcid":false,"given":"Natalia G.","family":"Rocha","sequence":"additional","affiliation":[{"name":"Laboratory of Exercise Science Department of Physiology and Pharmacology Fluminense Federal University  Niteroi Brazil"},{"name":"Laboratory of Integrative Cardiometabology Department of Physiology and Pharmacology Fluminense Federal University  Niteroi Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3830-2886","authenticated-orcid":false,"given":"Antonio C. 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