{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T15:49:01Z","timestamp":1764604141511,"version":"3.44.0"},"reference-count":32,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T00:00:00Z","timestamp":1754092800000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Hypertension"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Arterial hypertension often coexists with comorbidities that increase vascular damage. Although the primary goal is to reduce cardiovascular risk, the available risk scores can produce varying estimates. Here, we aim to compare the prevalence of cardiovascular risk categories using three equations (Globorisk, SCORE2, and PREVENT) in adults living with arterial hypertension and to assess their association as stratification tools for end\u2010organ damage (EOD). To achieve this, we performed a cross\u2010sectional sub\u2010analysis of the RIHTA study, an electronic health record\u2010based registry of adults with arterial hypertension in Mexican primary care centers. EOD was defined as aortic stiffness, reduced eGFR, hypertensive retinopathy, peripheral artery disease, or left ventricular hypertrophy. Inverse probability weighting (IPW) was used to evaluate the association between cardiovascular risk and EOD, adjusting for relevant confounders, and areas under the receiver operator curve (AUROC) were calculated to assess detection capacity. Among 4512 participants (median age 64\u00a0years; 61% women), EOD was present in 33% (<jats:italic>n<\/jats:italic>\u00a0=\u00a01492). The PREVENT equation yielded the highest median 10\u2010year risk (15%, IQR 8\u201324), followed by Globorisk laboratory\u2010based (12%, 7\u201322), Globorisk office\u2010based (11%, 7\u201319), and SCORE2 (5.06%, 3.86\u20137.18). In IPW models, each 1% increase in score was associated with higher odds of EOD (PREVENT OR 1.16, 95% CI 1.15\u20131.17; Globorisk\u2010office 1.09, 1.08\u20131.10; Globorisk\u2010lab 1.07, 1.06\u20131.08; SCORE2 1.04, 1.02\u20131.06). The PREVENT score demonstrated the strongest discrimination for detecting EOD (AUROC: 0.751, 0.735\u20130.750). These findings suggest that among adults with arterial hypertension, the PREVENT score identifies high\u2010risk individuals and improves discrimination for EOD.<\/jats:p>","DOI":"10.1111\/jch.70106","type":"journal-article","created":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T09:06:05Z","timestamp":1754125565000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Comparison of Globorisk, SCORE2, and PREVENT in the Stratification of Cardiovascular Risk and its Relationship with End\u2010Organ Damage Among Adults With Arterial Hypertension"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1047-5301","authenticated-orcid":false,"given":"Silvia","family":"Palomo\u2010Pi\u00f1\u00f3n","sequence":"first","affiliation":[{"name":"Grupo de Expertos en Hipertensi\u00f3n Arterial M\u00e9xico (GREHTA)  Ciudad de M\u00e9xico Mexico"},{"name":"Grupo Colaborativo en Hipertensi\u00f3n Arterial (GCHTA)  Ciudad de M\u00e9xico Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1657-1695","authenticated-orcid":false,"given":"Luis","family":"Alcocer","sequence":"additional","affiliation":[{"name":"Grupo de Expertos en Hipertensi\u00f3n Arterial M\u00e9xico (GREHTA)  Ciudad de M\u00e9xico Mexico"},{"name":"Hospital \u00c1ngeles del Pedregal  Ciudad de M\u00e9xico Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-5282-9834","authenticated-orcid":false,"given":"Humberto","family":"\u00c1lvarez\u2010L\u00f3pez","sequence":"additional","affiliation":[{"name":"Grupo de Expertos en Hipertensi\u00f3n Arterial M\u00e9xico (GREHTA)  Ciudad de M\u00e9xico Mexico"},{"name":"Hospital Puerta de Hierro Andares  Zapopan Jalisco Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7868-667X","authenticated-orcid":false,"given":"Ernesto G.","family":"Cardona\u2010Mu\u00f1oz","sequence":"additional","affiliation":[{"name":"Grupo de Expertos en Hipertensi\u00f3n Arterial M\u00e9xico (GREHTA)  Ciudad de M\u00e9xico Mexico"},{"name":"Centro Universitario de Ciencias de la Salud Universidad de Guadalajara  Guadalajara Jalisco Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1031-3946","authenticated-orcid":false,"given":"Adolfo","family":"Ch\u00e1vez\u2010Mendoza","sequence":"additional","affiliation":[{"name":"Grupo de Expertos en Hipertensi\u00f3n Arterial M\u00e9xico (GREHTA)  Ciudad de M\u00e9xico Mexico"},{"name":"Unidad M\u00e9dica de Alta Especialidad de Cardiolog\u00eda Centro M\u00e9dico Nacional SXXI Instituto Mexicano del Seguro Social  Ciudad de M\u00e9xico 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Mexico"},{"name":"Coordinaci\u00f3n Cl\u00ednica de Educaci\u00f3n e Investigaci\u00f3n en Salud Unidad de Medicina Familiar No. 55 Zumpango \u00d3rgano de Operaci\u00f3n Administrativa Desconcentrada Regional Estado de M\u00e9xico Oriente  Estado de M\u00e9xico Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6879-1078","authenticated-orcid":false,"given":"Neftali Eduardo","family":"Antonio\u2010Villa","sequence":"additional","affiliation":[{"name":"Grupo de Expertos en Hipertensi\u00f3n Arterial M\u00e9xico (GREHTA)  Ciudad de M\u00e9xico Mexico"},{"name":"Departamento de Endocrinolog\u00eda Instituto Nacional de Cardiolog\u00eda Ignacio Ch\u00e1vez  Ciudad de M\u00e9xico Mexico"},{"name":"Department of Global Health and Population Harvard T.H. Chan School of Public Health  Boston USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"the Mexican Group of Experts on Arterial Hypertension","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,8,2]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2020.18141"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2206916"},{"issue":"2","key":"e_1_2_14_4_1","first-page":"285","article-title":"High Blood Pressure and Cardiovascular Disease","volume":"75","author":"Fuchs F. 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