{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T11:49:47Z","timestamp":1764157787240,"version":"3.46.0"},"reference-count":28,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T00:00:00Z","timestamp":1762819200000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100017950","name":"Shanghai Municipal Health Commission","doi-asserted-by":"publisher","award":["202240082"],"award-info":[{"award-number":["202240082"]}],"id":[{"id":"10.13039\/100017950","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Hypertension"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Hypertensive disorders in pregnancy (HDP) are a major cause of maternal and perinatal morbidity and mortality. The impact of HDP on labor stage duration and maternal and neonatal outcomes in nulliparous women remains unclear. To assess labor stage duration and maternal and neonatal outcomes in nulliparous women with HDP. A retrospective cohort of 31\u00a0472 singleton pregnancies from January 2018 to December 2023 at the Obstetrics and Gynecology Hospital of Fudan University was analyzed using 1:4 propensity score matching (PSM) and inverse probability of treatment weighting (IPTW). Labor stage durations and maternal and neonatal outcomes were analyzed between women with and without HDP. HDP pregnancies had shorter first and total labor stages but longer second and third stages. The HDP group also had higher oxytocin (OCT) use, reduced fetal distress, intrapartum fever, and increased postpartum hemorrhage. Subgroup analysis by labor onset showed that for spontaneous onset, the HDP group had a significantly shorter first stage and total labor duration, with a significantly longer second and third stage duration. In subgroup analysis by HDP type, among pregnancies with spontaneous onset, those with superimposed preeclampsia on chronic hypertension had the shortest labor duration, followed by gestational hypertension and preeclampsia groups, with chronic hypertension alone showing the longest. Similarly, in the induced labor subgroup, gestational hypertension had the shortest duration, followed by superimposed preeclampsia and preeclampsia, with chronic hypertension again exhibiting the longest. The study indicates HDP affects labor duration, with implications for obstetric policies and childbirth safety.<\/jats:p>","DOI":"10.1111\/jch.70179","type":"journal-article","created":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T16:34:31Z","timestamp":1762878871000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Peripartum Management and Labor Stage Duration in Hypertensive Disorders in Pregnancy: A Retrospective Study in a Single Center"],"prefix":"10.1111","volume":"27","author":[{"given":"Hao","family":"Zhu","sequence":"first","affiliation":[{"name":"Obstetrics and Gynecology Hospital of Fudan University Shanghai Key Lab of Reproduction and Development Shanghai Key Lab of Female Reproductive Endocrine Related Diseases  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bian","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Medicine Tongji University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi","family":"Yu","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Hospital of Fudan University Shanghai Key Lab of Reproduction and Development Shanghai Key Lab of Female Reproductive Endocrine Related Diseases  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rong","family":"Hu","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Hospital of Fudan University Shanghai Key Lab of Reproduction and Development Shanghai Key Lab of Female Reproductive Endocrine Related Diseases  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weirong","family":"Gu","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Hospital of Fudan University Shanghai Key Lab of Reproduction and Development Shanghai Key Lab of Female Reproductive Endocrine Related Diseases  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,11,11]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_11_2_1","DOI":"10.1097\/AOG.0000000000003891"},{"doi-asserted-by":"publisher","key":"e_1_2_11_3_1","DOI":"10.1016\/S2214-109X(14)70227-X"},{"doi-asserted-by":"publisher","key":"e_1_2_11_4_1","DOI":"10.1016\/S0140-6736(09)60736-4"},{"volume-title":"WHO Recommendations: Policy of Interventionist Versus Expectant Management of Severe Preeclampsia Before Term","year":"2018","author":"WHO Guidelines Approved by the Guidelines Review Committee","key":"e_1_2_11_5_1"},{"doi-asserted-by":"publisher","key":"e_1_2_11_6_1","DOI":"10.1016\/j.preghy.2017.06.003"},{"doi-asserted-by":"publisher","key":"e_1_2_11_7_1","DOI":"10.1016\/j.ejogrb.2020.05.024"},{"doi-asserted-by":"publisher","key":"e_1_2_11_8_1","DOI":"10.1016\/j.preghy.2018.01.010"},{"doi-asserted-by":"publisher","key":"e_1_2_11_9_1","DOI":"10.1016\/S0020-7292(97)02854-3"},{"issue":"6","key":"e_1_2_11_10_1","first-page":"361","article-title":"Guideline of Normal Birth","volume":"55","author":"Obstetric Subgroup SoOaG, Association. CM, Perinatal. So, Association. MCM","year":"2020","journal-title":"Chinese Journal of Obstetrics and Gynecology"},{"doi-asserted-by":"publisher","key":"e_1_2_11_11_1","DOI":"10.1002\/ijgo.13862"},{"doi-asserted-by":"publisher","key":"e_1_2_11_12_1","DOI":"10.3390\/nu12061681"},{"doi-asserted-by":"publisher","key":"e_1_2_11_13_1","DOI":"10.1016\/S0140-6736(19)31282-6"},{"doi-asserted-by":"publisher","key":"e_1_2_11_14_1","DOI":"10.1111\/aogs.14406"},{"issue":"2","key":"e_1_2_11_15_1","first-page":"409","article-title":"ACOG Committee Opinion No. 767 Summary: Emergent Therapy for Acute\u2010Onset, Severe Hypertension During Pregnancy and the Postpartum Period","volume":"133","year":"2019","journal-title":"Obstetrics and Gynecology"},{"doi-asserted-by":"publisher","key":"e_1_2_11_16_1","DOI":"10.1097\/AOG.0000000000001246"},{"doi-asserted-by":"publisher","key":"e_1_2_11_17_1","DOI":"10.1080\/15513810600908461"},{"doi-asserted-by":"publisher","key":"e_1_2_11_18_1","DOI":"10.1016\/j.emc.2016.08.008"},{"doi-asserted-by":"publisher","key":"e_1_2_11_19_1","DOI":"10.1001\/jamanetworkopen.2023.20802"},{"doi-asserted-by":"publisher","key":"e_1_2_11_20_1","DOI":"10.1093\/ckj\/sfab158"},{"doi-asserted-by":"publisher","key":"e_1_2_11_21_1","DOI":"10.1016\/S0165-0378(97)00065-X"},{"doi-asserted-by":"publisher","key":"e_1_2_11_22_1","DOI":"10.1093\/molehr\/gaq014"},{"doi-asserted-by":"publisher","key":"e_1_2_11_23_1","DOI":"10.1097\/AOG.0000000000003470"},{"doi-asserted-by":"publisher","key":"e_1_2_11_24_1","DOI":"10.1016\/j.placenta.2014.03.013"},{"doi-asserted-by":"publisher","key":"e_1_2_11_25_1","DOI":"10.1016\/j.ajog.2014.04.027"},{"doi-asserted-by":"publisher","key":"e_1_2_11_26_1","DOI":"10.1152\/physrev.00019.2023"},{"doi-asserted-by":"publisher","key":"e_1_2_11_27_1","DOI":"10.1093\/molehr\/gaab024"},{"doi-asserted-by":"publisher","key":"e_1_2_11_28_1","DOI":"10.1097\/AOG.0000000000004228"},{"doi-asserted-by":"publisher","key":"e_1_2_11_29_1","DOI":"10.1097\/AOG.0000000000004824"}],"container-title":["The Journal of Clinical Hypertension"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jch.70179","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T11:45:30Z","timestamp":1764157530000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jch.70179"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":28,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["10.1111\/jch.70179"],"URL":"https:\/\/doi.org\/10.1111\/jch.70179","archive":["Portico"],"relation":{},"ISSN":["1524-6175","1751-7176"],"issn-type":[{"type":"print","value":"1524-6175"},{"type":"electronic","value":"1751-7176"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"2025-07-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-29","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-11","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70179"}}