{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T09:57:42Z","timestamp":1787997462157,"version":"build-2784847793"},"reference-count":16,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T00:00:00Z","timestamp":1776297600000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000056","name":"National Institute of Nursing Research","doi-asserted-by":"publisher","award":["R01NR014484"],"award-info":[{"award-number":["R01NR014484"]}],"id":[{"id":"10.13039\/100000056","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Hypertension"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Portable air cleaners (PACs) can reduce blood pressure (BP) by decreasing fine particulate matter (PM\n                    <jats:sub>2.5<\/jats:sub>\n                    ) air pollution exposure. However, the effectiveness of a single PAC in a bedroom and the impact on self\u2010measured home BPs over 4 weeks have not been evaluated. We conducted a randomized\u2010order double\u2010blind cross\u2010over trial of active PAC (HEPA filter in\u2010place) versus sham (no filter) intervention in the bedroom of older adults living in a senior residential facility from 1\/11\/2021\u201011\/4\/2024. Each study limb lasted 4 weeks with a 2\u2010week washout period. Participants measured triplicate home BPs in the mornings and evenings during weeks 1 and 4. Bedroom PM\n                    <jats:sub>2.5<\/jats:sub>\n                    concentrations were continuously monitored, and 24\u2010h personal exposures were determined during week 4. Results from 33 participants (74.9\u00a0\u00b1\u00a07.7 years old) completing the trial were analyzed. Active PAC intervention reduced bedroom PM\n                    <jats:sub>2.5<\/jats:sub>\n                    concentrations (1.3\u00b11.5 vs. 8.3\u00b112.8\u00a0\u00b5g\/m\n                    <jats:sup>3<\/jats:sup>\n                    ,\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0&lt;\u00a00.001) and 24\u2010h personal exposures (5.1\u00a0\u00b1\u00a04.6 vs. 12.4\u00b115.6\u00a0\u00b5g\/m\n                    <jats:sup>3<\/jats:sup>\n                    ,\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0&lt;\u00a00.001) versus sham. Average home systolic BP levels did not differ during active PAC versus sham intervention in the full study cohort (127.0\u00a0\u00b1\u00a016.2 vs. 126.5\u00a0\u00b1\u00a016.0\u00a0mm Hg,\n                    <jats:italic>p<\/jats:italic>\n                    = 0.59). However, having a larger body mass index plus higher baseline systolic BP, older age plus higher baseline systolic BP, and older age plus larger body mass index showed trends for modifying the benefits by active PAC. We showed for the first time that air filtration in the bedroom alone can successfully reduce PM\n                    <jats:sub>2.5<\/jats:sub>\n                    exposures. While systolic BPs were not lowered over 4 weeks in the entire cohort, some individuals may have benefited.\n                  <\/jats:p>","DOI":"10.1111\/jch.70251","type":"journal-article","created":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T10:50:41Z","timestamp":1776336641000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Bedroom Air Filtration and Home Blood Pressures of Older Adults Living in a Residential Facility"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8521-7262","authenticated-orcid":false,"given":"Robert D.","family":"Brook","sequence":"first","affiliation":[{"name":"Division of Cardiovascular Diseases Wayne State University  Detroit MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, School of Public Health University of Michigan  Ann Arbor MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert L.","family":"Bard","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine University of Michigan  Ann Arbor MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, School of Public Health University of Michigan  Ann Arbor MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zachary M.","family":"Klaver","sequence":"additional","affiliation":[{"name":"Exposure Science Lab, Department of Family Medicine, College of Human Medicine Michigan State University  East Lansing MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosemary A.","family":"Ziemba","sequence":"additional","affiliation":[{"name":"Community Health Nursing  Ann Arbor MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geoffrey D.","family":"Barnes","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine University of Michigan  Ann Arbor MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alec J.","family":"Brook","sequence":"additional","affiliation":[{"name":"Wayne State Medical School  Detroit MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda","family":"Keilman","sequence":"additional","affiliation":[{"name":"College of Nursing Michigan State University  East Lansing MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masako","family":"Morishita","sequence":"additional","affiliation":[{"name":"Exposure Science Lab, Department of Family Medicine, College of Human Medicine Michigan State University  East Lansing MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,16]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2018.07.099"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.124.18733"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.123.20617"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.122.029206"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000931"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoenv.2023.115227"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2018.3308"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41370-018-0085-2"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0000000000003653"},{"issue":"10","key":"e_1_2_13_11_1","first-page":"e212","article-title":"2025 AHA\/ACC\/AANP\/AAPA\/ABC\/ACCP\/ACPM\/AGS\/AMA\/ASPC\/NMA\/PCNA\/SGIM Guideline for the Prevention, Detection, Evaluation and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology\/American Heart Association Joint Committee on Clinical Practice Guidelines","volume":"82","author":"Jones D. W.","year":"2025","journal-title":"Hypertension"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2542-5196(21)00131-5"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-021-04190-y"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2025.06.037"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/HCR.0000000000000516"},{"key":"e_1_2_13_16_1","unstructured":"US Bureau of Labor Statistics(https:\/\/www.bls.gov\/news.release\/atus.htm)."},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1029\/2021GH000482"}],"container-title":["The Journal of Clinical Hypertension"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jch.70251","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jch.70251","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jch.70251","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T05:48:53Z","timestamp":1777355333000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jch.70251"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":16,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["10.1111\/jch.70251"],"URL":"https:\/\/doi.org\/10.1111\/jch.70251","archive":["Portico"],"relation":{},"ISSN":["1524-6175","1751-7176"],"issn-type":[{"value":"1524-6175","type":"print"},{"value":"1751-7176","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"2025-12-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-16","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70251"}}