{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T14:17:21Z","timestamp":1783693041252,"version":"3.55.0"},"reference-count":37,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T00:00:00Z","timestamp":1781481600000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["NSFC 82304166"],"award-info":[{"award-number":["NSFC 82304166"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2024A1515010592"],"award-info":[{"award-number":["2024A1515010592"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Hypertension"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    The association of atherogenic index of plasma (AIP) control level with hypertension onset in children was still unclear. This study aimed to investigate the association between AIP control levels and risk of childhood hypertension. We obtained data from 12,800 students participating in a national, multi\u2010center, school\u2010based health lifestyle intervention program aimed at combating obesity. AIP was calculated using the formula log\n                    <jats:sub>10<\/jats:sub>\n                    (TG\/HDL\u2010C), and was categorized into five clusters based on baseline and 1\u00a0year follow\u2010up values. Logistic regression and restricted cubic spline regression models were employed to explore both linear and nonlinear associations between AIP control and hypertension risk. Of the 12,800 students, 830 (6.5%) developed hypertension within 1\u00a0year. Compared to the group with optimal AIP control (Class 1), students in Class 4 with poor AIP control (\n                    <jats:italic>OR<\/jats:italic>\n                    \u00a0=\u00a01.75; 95% CI: 1.31\u20132.33;\n                    <jats:italic>p\u00a0<\/jats:italic>\n                    &lt;\u00a00.001), and those in Class 5 with the worst AIP control (\n                    <jats:italic>OR<\/jats:italic>\n                    \u00a0=\u00a02.43; 95% CI: 1.69\u20133.50;\n                    <jats:italic>p\u00a0<\/jats:italic>\n                    &lt;\u00a00.001), had higher incidences of hypertension. Restricted cubic spline regression analysis revealed a nonlinear relationship between AIP control and hypertension risk overall, and in Class 4 (\n                    <jats:italic>p<\/jats:italic>\n                    for nonlinear &lt;0.05). However, the association was linear in the other classes (\n                    <jats:italic>p<\/jats:italic>\n                    for nonlinear &gt;0.05). In conclusion, the level of AIP control was associated with the incidence of hypertension in children and adolescents.\n                  <\/jats:p>","DOI":"10.1111\/jch.70303","type":"journal-article","created":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T03:41:47Z","timestamp":1781581307000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Association Between Plasma Atherogenic Index Control Level and the Onset of Hypertension in Chinese Children and Adolescents"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0780-0604","authenticated-orcid":false,"given":"Rong","family":"Lian","sequence":"first","affiliation":[{"name":"School of Medicine Guangzhou First People's Hospital, South China University of Technology  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi\u2010de","family":"Yang","sequence":"additional","affiliation":[{"name":"Hunan Normal University School of Public Health  Hunan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xi\u2010jie","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Disaster and Emergency Medicine Tianjin University  Tianjin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Man\u2010man","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Population Medicine and Public Health Chinese Academy of Medical Sciences and Peking Union Medical College  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3529-1808","authenticated-orcid":false,"given":"Jun","family":"Ma","sequence":"additional","affiliation":[{"name":"School of Public Health &amp; Institute of Child and Adolescent Health Peking University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zheng\u2010he","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Epidemiology School of Public Health Southern Medical University  Guangzhou Guangdong China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,15]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213\u20108587(14)70102\u20100"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(16)31919\u20105"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41581\u2010019\u20100244\u20102"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.115.018912"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0895\u20107061(95)00116\u20107"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.290.17.2277"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a116217"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2019.3310"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/07853890.2023.2267572"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12519\u2010022\u201000626\u20101"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2352\u20104642(25)00302\u20105"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11883\u2010023\u201001132\u2010z"},{"key":"e_1_2_13_14_1","first-page":"240","article-title":"Atherogenic Index of Plasma (AIP): A Marker of Cardiovascular Disease","volume":"29","author":"Niroumand S.","year":"2015","journal-title":"Medical Journal of the Islamic Republic of Iran"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12933\u2010023\u201001762\u20102"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa021993"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.5603\/KP.a2015.0086"},{"issue":"3","key":"e_1_2_13_18_1","first-page":"248","article-title":"Atherogenic Index of Plasma as Useful Predictor of Cardiovascular Risk Among Postmenopausal Women in Enugu","volume":"10","author":"Nwagha U. 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