{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T04:17:23Z","timestamp":1787804243852,"version":"build-2784847793"},"reference-count":21,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T00:00:00Z","timestamp":1786320000000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Hypertension"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Pheochromocytoma typically presents with sustained or paroxysmal hypertension, but initial manifestation as acute non\u2010ST\u2010segment elevation myocardial infarction (NSTEMI) is rare. Peri\u2010procedural hemodynamic fluctuations are often dramatic, making diagnosis and management challenging. We report a 51\u2010year\u2010old male admitted with chest tightness for 17 days. Elevated troponin and coronary angiography showing multivessel disease with total occlusion of the mid\u2010left anterior descending artery (LAD) led to a preliminary diagnosis of NSTEMI. During percutaneous coronary intervention, blood pressure surged to 240\/130\u00a0mmHg; intravenous nitroprusside caused an instantaneous drop to 95\/55\u00a0mmHg, with rapid rebound to &gt;200\u00a0mmHg upon withdrawal, showing no clear temporal relationship with drug administration. Postoperatively, large rapid blood pressure oscillations persisted, associated with postural changes but without patient discomfort. Workup revealed markedly elevated plasma catecholamines: dopamine 77.58 pg\/mL (normal 0\u201320), normetanephrine 1881.63 pg\/mL (0\u2013145), and norepinephrine 5,724.04 pg\/mL (217\u20131,109). CT and PET\u2010CT identified a left retroperitoneal mass (59\u00d734\u00d744\u00a0mm, SUVmax 14.6), suggestive of pheochromocytoma. Surgical resection was performed, and histopathology with immunohistochemistry confirmed the diagnosis. Postoperatively, the patient required no antihypertensive medications and blood pressure remained stable. This case illustrates a rare pheochromocytoma presentation as secondary hypertension manifesting as acute myocardial infarction, characterized by extreme peri\u2010procedural hemodynamic instability during PCI and an \u201call\u2010or\u2010none\u201d response to conventional antihypertensive therapy, ultimately cured by surgical resection.<\/jats:p>","DOI":"10.1111\/jch.70332","type":"journal-article","created":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T09:44:59Z","timestamp":1786355099000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Case Report of Myocardial Infarction Complicated With Blood Pressure Fluctuations Caused by Pheochromocytoma"],"prefix":"10.1111","volume":"28","author":[{"given":"HuiPing","family":"Li","sequence":"first","affiliation":[{"name":"Department of Cardiology Fuwai Central China Cardiovascular Hospital, Central China Fuwai Hospital of Zhengzhou University  Zhengzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Cardiology Fuwai Central China Cardiovascular Hospital, Central China Fuwai Hospital of Zhengzhou University  Zhengzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Feng","sequence":"additional","affiliation":[{"name":"Department of Cardiology Fuwai Central China Cardiovascular Hospital, Central China Fuwai Hospital of Zhengzhou University  Zhengzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"You","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Cardiology Fuwai Central China Cardiovascular Hospital, Central China Fuwai Hospital of Zhengzhou University  Zhengzhou China"},{"name":"Henan Institute of Cardiovascular Epidemiology  Zhengzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ganxin","family":"Yan","sequence":"additional","affiliation":[{"name":"Lankenau Institute for Medical Research, Main Line Health Heart Center, Jefferson Medical College of Thomas Jefferson University  Wynnewood Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ChuanYu","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Cardiology Fuwai Central China Cardiovascular Hospital, Central China Fuwai Hospital of Zhengzhou University  Zhengzhou China"},{"name":"Henan Key Laboratory of Coronary Heart Disease Control &amp; Prevention Central China Fuwai Hospital  Zhengzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,10]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehy462"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2019.02.018"},{"issue":"10","key":"e_1_2_9_4_1","first-page":"766","article-title":"Guideline on the Diagnosis and Therapy of ST\u2010Segment Elevation Myocardial Infarction","volume":"47","author":"Chinese Society of Cardiology of Chinese Medical Association, Editorial Board of Chinese Journal of Cardiology","year":"2019","journal-title":"Chinese Journal of Cardiovascular Diseases"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11883-021-00945-0"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehab581"},{"issue":"9","key":"e_1_2_9_7_1","first-page":"737","article-title":"Expert Consensus on Diagnosis and Treatment of Pheochromocytoma and Paraganglioma (2020 edition)","volume":"36","author":"Chinese Society of Endocrinology","year":"2020","journal-title":"Chinese Journal of Endocrinology and Metabolism"},{"issue":"8","key":"e_1_2_9_8_1","article-title":"Catecholamine\u2010Induced Cardiomyopathy in Pheochromocytoma: A Systematic Review","volume":"11","author":"Santos J. 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F.","year":"2024","journal-title":"West China Medicine"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2022.879714"},{"issue":"8","key":"e_1_2_9_13_1","first-page":"1528","article-title":"Pheochromocytoma Crisis: A Review of Literature","volume":"23","author":"Gogia S.","year":"2021","journal-title":"Journal of Clinical Hypertension"},{"issue":"7","key":"e_1_2_9_14_1","first-page":"458","article-title":"Catecholamine\u2010Induced Cardiomyopathy in Pheochromocytoma: How to Manage a Rare Complication in a Rare Disease?","volume":"50","author":"Santos J. R. 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