{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T04:17:22Z","timestamp":1787804242395,"version":"build-2784847793"},"reference-count":37,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,8,15]],"date-time":"2026-08-15T00:00:00Z","timestamp":1786752000000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81373014"],"award-info":[{"award-number":["81373014"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007937","name":"Peking University","doi-asserted-by":"publisher","award":["U01 DD000293"],"award-info":[{"award-number":["U01 DD000293"]}],"id":[{"id":"10.13039\/501100007937","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Hypertension"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>A recent study suggested an increase in male births associated with maternal preconception high blood pressure. Our objective was to examine this association. Data were obtained from the China\u2010US Collaborative Project for Neural Tube Defects Prevention, a large population\u2010based cohort study. We included 44\u00a0399 singleton pregnancy to women who were registered before pregnancy in seven counties in southern China. Blood pressure was measured during registration by trained health care workers and other health\u2010related information was recorded prospectively. We used log\u2010binomial regression to evaluate the associations between preconception blood pressure and the risk of male delivery, adjusting for potential confounders. The study size had 99% power (\u03b1 = 0.05) to detect an increase of 50% over the unexposed rate of 51.94% for male delivery. The prevalence of hypertension in the preconception study population was 4.61% (2045\/44\u00a0399). The prevalence of male delivery was 51.10% for the hypertension group and 51.79% for the non\u2010hypertension group. Compared with the non\u2010hypertension group, the hypertension group did not show significantly increased chance for male delivery [adjusted risk ratio (RR) = 0.99, 95% confidence interval (CI): 0.94, 1.03]. Our results do not support an association between hypertension or higher blood pressure prior to pregnancy and increased likelihood of male delivery.<\/jats:p>","DOI":"10.1111\/jch.70349","type":"journal-article","created":{"date-parts":[[2026,8,16]],"date-time":"2026-08-16T02:40:47Z","timestamp":1786848047000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Preconception Blood Pressure and Sex of the Baby: A Large Prospective Cohort Study in China"],"prefix":"10.1111","volume":"28","author":[{"given":"Yiran","family":"Wang","sequence":"first","affiliation":[{"name":"Institute of Reproductive and Child Health Chinese National Health Commission Key Laboratory of Reproductive Health Peking University Health Science Center  Beijing China"},{"name":"Department of Epidemiology and Biostatistics School of Public Health Peking University Health Science Center  Beijing 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