{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T03:54:45Z","timestamp":1791172485393,"version":"4.1.0"},"reference-count":33,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T00:00:00Z","timestamp":1789171200000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82472008"],"award-info":[{"award-number":["82472008"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Hypertension"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    This study investigated the correlation of functional hemodynamic parameters, including subendocardial viability ratio (SEVR), augmentation pressure (AP) and heart\u2010rate\u2010corrected augmentation index (Aix@75), with age and atherosclerotic cardiovascular disease (ASCVD) risk in a Chinese population. A total of 3,354 participants aged 18\u201380 years with left ventricular ejection fraction &gt;55% were enrolled in this cross\u2010sectional study. Functional hemodynamic parameters were assessed by pulse wave analysis, and the 10\u2010year ASCVD risk (10Y\u2010ASCVDR) was estimated using the China\u2010PAR model. Multivariable logistic regression was used to identify independent correlates of elevated estimated 10Y\u2010ASCVDR. Results showed that 10Y\u2010ASCVDR was inversely correlated with SEVR (\n                    <jats:italic>r =<\/jats:italic>\n                    \u20130.171,\n                    <jats:italic>p &lt;<\/jats:italic>\n                    0.001) and positively correlated with AP (\n                    <jats:italic>r =<\/jats:italic>\n                    0.452,\n                    <jats:italic>p &lt;<\/jats:italic>\n                    0.001) and Aix@75 (\n                    <jats:italic>r =<\/jats:italic>\n                    0.236,\n                    <jats:italic>p &lt;<\/jats:italic>\n                    0.001). Stepwise multivariable linear regression identified SEVR, AP and Aix@75 as\u00a0independent correlates of estimated 10\u2010year ASCVD risk (\n                    <jats:italic>p &lt;<\/jats:italic>\n                    0.001). In conclusion, SEVR, AP and Aix@75 are independent correlates of estimated 10\u2010year ASCVD risk, and together provide a functional hemodynamic profile that independently correlates with estimated risk beyond traditional factors, suggesting their potential role as supplementary tools for cardiovascular risk stratification. These findings offer a valuable supplemental approach for improving cardiovascular risk assessment in clinical practice.\n                  <\/jats:p>","DOI":"10.1111\/jch.70364","type":"journal-article","created":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T09:32:28Z","timestamp":1789205548000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Functional Markers of Vascular Aging: Subendocardial Viability Ratio, Augmentation Pressure, and Augmentation Index as Links to Atherosclerotic Cardiovascular Disease Risk"],"prefix":"10.1111","volume":"28","author":[{"given":"Lan","family":"Yang","sequence":"first","affiliation":[{"name":"College of Laboratory Medicine Chengdu Medical College  Chengdu Sichuan P.R. China"},{"name":"Department of Ultrasound Shanghai Children's Hospital Shanghai Jiao Tong University School of Medicine  Shanghai Shanghai P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingxiao","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Changhai Hospital Naval Medical University  Shanghai Shanghai P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Shanghai General Hospital Shanghai Jiaotong University School of Medicine  Shanghai Shanghai P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ning","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Shanghai General Hospital Shanghai Jiaotong University School of Medicine  Shanghai Shanghai P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Shanghai General Hospital of Nanjing Medical University  Shanghai Shanghai P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianyu","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Shanghai General Hospital of Nanjing Medical University  Shanghai Shanghai P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huiyong","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Shanghai Children's Hospital Shanghai Jiao Tong University School of Medicine  Shanghai Shanghai P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hairong","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Shanghai Children's Hospital Shanghai Jiao Tong University School of Medicine  Shanghai Shanghai P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianghong","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Echocardiography Shanghai General Hospital Shanghai Jiaotong University School of Medicine  Shanghai Shanghai P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6459-3667","authenticated-orcid":false,"given":"Zhaojun","family":"Li","sequence":"additional","affiliation":[{"name":"College of Laboratory Medicine Chengdu Medical College  Chengdu Sichuan P.R. China"},{"name":"Department of Ultrasound Shanghai Children's Hospital Shanghai Jiao Tong University School of Medicine  Shanghai Shanghai P.R. China"},{"name":"Department of Ultrasound Shanghai General Hospital Shanghai Jiaotong University School of Medicine  Shanghai Shanghai P.R. China"},{"name":"Department of Ultrasound Shanghai General Hospital of Nanjing Medical University  Shanghai Shanghai P.R. 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