{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:48:44Z","timestamp":1787168924171,"version":"build-2736575974"},"reference-count":56,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2013,11,4]],"date-time":"2013-11-04T00:00:00Z","timestamp":1383523200000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cellular Molecular Medi"],"published-print":{"date-parts":[[2013,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Telocytes (\n                    <jats:styled-content style=\"fixed-case\">TC<\/jats:styled-content>\n                    s), a new type of interstitial cells, were identified in many different organs and tissues of mammalians and humans. In this study, we show the presence, in human oesophagus, of cells having the typical features of\n                    <jats:styled-content style=\"fixed-case\">TC<\/jats:styled-content>\n                    s in lamina propria of the mucosa, as well as in muscular layers. We used transmission electron microscopy (\n                    <jats:styled-content style=\"fixed-case\">TEM<\/jats:styled-content>\n                    ), immunohistochemistry (\n                    <jats:styled-content style=\"fixed-case\">IHC<\/jats:styled-content>\n                    ) and primary cell culture. Human oesophageal\n                    <jats:styled-content style=\"fixed-case\">TC<\/jats:styled-content>\n                    s present a small cell body with 2\u20133 very long Telopodes (Tps). Tps consist of an alternation of thin segments (\n                    <jats:italic>podomers<\/jats:italic>\n                    ) and thick segments (\n                    <jats:italic>podoms<\/jats:italic>\n                    ) and have a labyrinthine spatial arrangement. Tps establish close contacts (\u2018stromal synapses\u2019) with other neighbouring cells (\n                    <jats:italic>e.g<\/jats:italic>\n                    . lymphocytes, macrophages). The\n                    <jats:styled-content style=\"fixed-case\">ELISA<\/jats:styled-content>\n                    testing of the supernatant of primary culture of\n                    <jats:styled-content style=\"fixed-case\">TC<\/jats:styled-content>\n                    s indicated that the concentrations of\n                    <jats:styled-content style=\"fixed-case\">VEGF<\/jats:styled-content>\n                    and\n                    <jats:styled-content style=\"fixed-case\">EGF<\/jats:styled-content>\n                    increased progressively. In conclusion, our study shows the existence of typical\n                    <jats:styled-content style=\"fixed-case\">TC<\/jats:styled-content>\n                    s at the level of oesophagus (mucosa, submucosa and muscular layer) and suggests their possible role in tissue repair.\n                  <\/jats:p>","DOI":"10.1111\/jcmm.12149","type":"journal-article","created":{"date-parts":[[2013,11,4]],"date-time":"2013-11-04T22:14:50Z","timestamp":1383603290000},"page":"1506-1512","source":"Crossref","is-referenced-by-count":65,"title":["Telocytes in human oesophagus"],"prefix":"10.1111","volume":"17","author":[{"given":"Xiaoke","family":"Chen","sequence":"first","affiliation":[{"name":"Department of thoracic surgery Zhongshan Hospital Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yonghua","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catalin G.","family":"Manole","sequence":"additional","affiliation":[{"name":"Department of Cellular and Molecular Medicine \u2018Carold Davila\u2019 University of Medicine and Pharmacy Bucharest Romania"},{"name":"Molecular Medicine National Institute of Pathology Bucharest Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangdong","family":"Wang","sequence":"additional","affiliation":[{"name":"Biomedical Research Center Zhongshan Hospital Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qun","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of thoracic surgery Zhongshan Hospital Fudan University Shanghai 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