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Our previous data demonstrated patterns of mouse <jats:styled-content style=\"fixed-case\">TC<\/jats:styled-content>\u2010specific gene profiles on chromosome 1. The present study focuses on the identification of characters and patterns of <jats:styled-content style=\"fixed-case\">TC<\/jats:styled-content>\u2010specific or <jats:styled-content style=\"fixed-case\">TC<\/jats:styled-content>\u2010dominated gene expression profiles in chromosome 2 and 3, the network of principle genes and potential functional association. 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Obvious overexpression of Myl9 in chromosome 2 of <jats:styled-content style=\"fixed-case\">TC<\/jats:styled-content>s different from other cells, indicates that biological functions of <jats:styled-content style=\"fixed-case\">TC<\/jats:styled-content>s are mainly associated with tissue\/organ injury and ageing, while down\u2010expression of Pltp implies that <jats:styled-content style=\"fixed-case\">TC<\/jats:styled-content>s may be associated with inhibition or reduction of inflammation in the lung. Dominant overexpression of Sh3glb1, Tm4sf1 or Csf1 in chromosome 3 of <jats:styled-content style=\"fixed-case\">TC<\/jats:styled-content>s is mainly associated with tumour promotion in lung cancer, while most down\u2010expression of Pde5 may be involved in the development of pulmonary fibrosis and other acute and chronic interstitial lung disease.<\/jats:p>","DOI":"10.1111\/jcmm.12429","type":"journal-article","created":{"date-parts":[[2014,10,2]],"date-time":"2014-10-02T12:43:16Z","timestamp":1412253796000},"page":"2044-2060","source":"Crossref","is-referenced-by-count":53,"title":["Variations of chromosomes 2 and 3 gene expression profiles among pulmonary telocytes, pneumocytes, airway cells, mesenchymal stem cells and lymphocytes"],"prefix":"10.1111","volume":"18","author":[{"given":"Minghuan","family":"Zheng","sequence":"first","affiliation":[{"name":"Biomedical Research Center Minhang Hospital &amp; Zhongshan Hospital Fudan University Center for Clinical Bioinformatics Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoru","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine The First affiliated Hospital Wenzhou Medical University Wenzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miaomiao","family":"Zhang","sequence":"additional","affiliation":[{"name":"Biomedical Research Center Minhang Hospital &amp; Zhongshan Hospital Fudan University Center for Clinical Bioinformatics Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mengjia","family":"Qian","sequence":"additional","affiliation":[{"name":"Biomedical Research Center Minhang Hospital &amp; Zhongshan Hospital Fudan University Center for Clinical Bioinformatics Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yonghua","family":"Zheng","sequence":"additional","affiliation":[{"name":"Biomedical Research Center Minhang Hospital &amp; Zhongshan Hospital Fudan University Center for Clinical Bioinformatics Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meiyi","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Lab of Systems Biology Chinese Academy of Science Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanda M.","family":"Cretoiu","sequence":"additional","affiliation":[{"name":"Department of Cell Biology and Histology Carol Davila University of Medicine and Pharmacy Bucharest Romania"},{"name":"Victor Babe\u015f National Institute of Pathology Bucharest Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chengshui","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine The First affiliated Hospital Wenzhou Medical University Wenzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luonan","family":"Chen","sequence":"additional","affiliation":[{"name":"State Key Lab of Systems Biology Chinese Academy of Science Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dragos","family":"Cretoiu","sequence":"additional","affiliation":[{"name":"Department of Cell Biology and Histology Carol Davila University of Medicine and Pharmacy Bucharest Romania"},{"name":"Victor Babe\u015f National Institute of Pathology Bucharest Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurentiu M.","family":"Popescu","sequence":"additional","affiliation":[{"name":"Department of Cell Biology and Histology Carol Davila University of Medicine and Pharmacy Bucharest Romania"},{"name":"Victor Babe\u015f National Institute of Pathology Bucharest Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hao","family":"Fang","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Zhongshan Hospital and Jinshan Hospital of Fudan University Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiangdong","family":"Wang","sequence":"additional","affiliation":[{"name":"Biomedical Research Center Minhang Hospital &amp; Zhongshan Hospital Fudan University Center for Clinical Bioinformatics Shanghai China"},{"name":"Department of Pulmonary Medicine The First affiliated Hospital Wenzhou Medical University Wenzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,10,2]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1582-4934.2010.01059.x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000319467"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2013.00278"},{"key":"e_1_2_7_5_1","first-page":"831","article-title":"CD34+ stromal cells\/fibroblasts\/fibrocytes\/telocytes as a tissue reserve and a principal source of mesenchymal cells. 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