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Systemic manifestations of patients with <jats:styled-content style=\"fixed-case\">PCNSL<\/jats:styled-content> keep backward in spite of recent development of chemoradiotherapy. Micro<jats:styled-content style=\"fixed-case\">RNA<\/jats:styled-content>s are small non\u2010coding <jats:styled-content style=\"fixed-case\">RNA<\/jats:styled-content>s that can post\u2010transcriptionally down\u2010regulate the expression of genes by targeting <jats:styled-content style=\"fixed-case\">mRNA<\/jats:styled-content>s, causing their translational repression as well as degradation. Micro<jats:styled-content style=\"fixed-case\">RNA<\/jats:styled-content>s exert critical functions in many malignancy\u2010related biological processes, including cell apoptosis, metabolism, proliferation and differentiation. Many deregulated mi<jats:styled-content style=\"fixed-case\">RNA<\/jats:styled-content>s have been identified in oesophageal adenocarcinomas, but their biological importance has not yet been fully elucidated. In this study, we review present evidence regarding the potential applications of oesophageal adenocarcinomas associated micro<jats:styled-content style=\"fixed-case\">RNA<\/jats:styled-content>s for prognosis and diagnosis of this lethal disease.<\/jats:p>","DOI":"10.1111\/jcmm.13300","type":"journal-article","created":{"date-parts":[[2017,8,11]],"date-time":"2017-08-11T03:42:42Z","timestamp":1502422962000},"page":"123-130","source":"Crossref","is-referenced-by-count":3,"title":["Expression signatures and roles of Micro<scp>RNA<\/scp>s in human oesophageal adenocarcinomas"],"prefix":"10.1111","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8209-042X","authenticated-orcid":false,"given":"Xiangyi","family":"Kong","sequence":"first","affiliation":[{"name":"Department of Neurosurgery Peking Union Medical College Hospital Chinese Academy of Medical Sciences Beijing China"},{"name":"Department of Breast Oncology National Cancer Center\/Cancer Hospital Peking Union Medical 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