{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T11:46:20Z","timestamp":1792669580320,"version":"4.5.0"},"reference-count":95,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,10,23]],"date-time":"2018-10-23T00:00:00Z","timestamp":1540252800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Cellular Molecular Medi"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Coronary artery stenting following balloon angioplasty represents the gold standard in revascularization of coronary artery stenoses. However, stent deployment as well as percutaneous transluminal coronary angioplasty (\n                    <jats:styled-content style=\"fixed-case\">PTCA<\/jats:styled-content>\n                    ) alone causes severe injury of vascular endothelium. The damaged endothelium is intrinsically repaired by locally derived endothelial cells and by circulating endothelial progenitor cells from the blood, leading to re\u2010population of the denuded regions within several weeks to months. However, the process of re\u2010endothelialization is often incomplete or dysfunctional, promoting in\u2010stent thrombosis and restenosis. The molecular and biomechanical mechanisms that influence the process of re\u2010endothelialization in stented segments are incompletely understood. Once the endothelium is restored, endothelial function might still be impaired. Several strategies have been followed to improve endothelial function after coronary stenting. In this review, the effects of stenting on coronary endothelium are outlined and current and future strategies to improve endothelial function after stent deployment are discussed.\n                  <\/jats:p>","DOI":"10.1111\/jcmm.13936","type":"journal-article","created":{"date-parts":[[2018,10,24]],"date-time":"2018-10-24T00:20:49Z","timestamp":1540340449000},"page":"39-46","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":106,"title":["The effects of stenting on coronary endothelium from a molecular biological view: Time for improvement?"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5452-4657","authenticated-orcid":false,"given":"Anne","family":"Cornelissen","sequence":"first","affiliation":[{"name":"Department of Cardiology, Pneumology, Angiology, and Internal Intensive Medicine University Hospital Aachen Aachen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix Jan","family":"Vogt","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Pneumology, Angiology, and Internal Intensive Medicine University Hospital Aachen Aachen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,10,23]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.61.4.778"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(80)80009-9"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198108133050706"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00012.2005"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00441-008-0659-8"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2009.01.004"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/327524a0"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.9.4888"},{"key":"e_1_2_9_10_1","first-page":"V51","article-title":"The endothelium as a regulator of vascular smooth muscle proliferation","volume":"87","author":"Scott\u2010Burden T","year":"1993","journal-title":"Circulation"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(94)90433-2"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.90.3.1357"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199508103330607"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.60.3.422"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199007053230106"},{"key":"e_1_2_9_16_1","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/S0308-2261(21)00487-2","article-title":"The role of endothelium in the homeostatic balance of haemostasis","volume":"14","author":"Nawroth P","year":"1985","journal-title":"Clin Haematol"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.med.47.1.315"},{"key":"e_1_2_9_18_1","first-page":"293","article-title":"Pharmacology and endogenuous roles of prostaglandin endoperoxides, thromboxane A2 and prostacyclin","volume":"79","author":"Moncada S","year":"1979","journal-title":"Pharmacol Rev"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0049-3848(98)90001-9"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199901143400207"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004872-200502000-00001"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2010.05599.x"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-1716.2009.01964.x"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/0046-8177(89)90014-2"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.2.2.125"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.61.1.77"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncpcardio1397"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvt090"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1093\/bmb\/ldt009"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(83)90326-0"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.75.1.243"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.75.3.636"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.79.6.1374"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(85)80174-1"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.10.6.966"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/s003950050180"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.94.1.35"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(01)01374-2"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199405193302008"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.3941904"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.16.10.1256"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.65.3.740"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI114665"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.85.3.221"},{"key":"e_1_2_9_45_1","first-page":"569","article-title":"Endothelial regeneration. V. Inhibition of endothelial regrowth in arteries of rat and rabbit","volume":"49","author":"Reidy MA","year":"1983","journal-title":"Lab Invest"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.03.042"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.693739"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2010.05.066"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2010.01.021"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.762047"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.104.508937"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.88.9.3739"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm0897-879"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(96)82370-9"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10439-009-9719-9"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.1186\/1475-925X-5-40"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.1615\/JLongTermEffMedImplants.v10.i12.120"},{"key":"e_1_2_9_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.04.030"},{"key":"e_1_2_9_59_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.115.002427"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.103.23.2816"},{"key":"e_1_2_9_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(03)00119-0"},{"key":"e_1_2_9_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(98)00348-9"},{"key":"e_1_2_9_63_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.86.8.892"},{"key":"e_1_2_9_64_1","doi-asserted-by":"publisher","DOI":"10.1038\/21218"},{"key":"e_1_2_9_65_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.110.957654"},{"key":"e_1_2_9_66_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrcardio.2012.64"},{"key":"e_1_2_9_67_1","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.1997.6772"},{"key":"e_1_2_9_68_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.95.2.438"},{"key":"e_1_2_9_69_1","first-page":"688","article-title":"Vascular endothelial growth factor (VEG\u2010F)\u2010eluting stents: in\u00a0vivo effects on thrombosis, endothelialization and intimal hyperplasia","volume":"15","author":"Swanson N","year":"2003","journal-title":"J Invasive Cardiol"},{"key":"e_1_2_9_70_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.22928"},{"key":"e_1_2_9_71_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00392-013-0547-4"},{"key":"e_1_2_9_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2012.08.066"},{"key":"e_1_2_9_73_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.0000114236.77009.06"},{"key":"e_1_2_9_74_1","doi-asserted-by":"publisher","DOI":"10.5551\/jat.31062"},{"key":"e_1_2_9_75_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJV3I3A64"},{"key":"e_1_2_9_76_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehp476"},{"key":"e_1_2_9_77_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.109.919936"},{"key":"e_1_2_9_78_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2012.08.306"},{"key":"e_1_2_9_79_1","doi-asserted-by":"publisher","DOI":"10.1586\/17434440.2014.882046"},{"key":"e_1_2_9_80_1","first-page":"311","article-title":"Study of a novel coating strategy for coronary stents: evaluation of stainless metallic steel coated with VEGF and anti\u2010CD34 antibody in\u00a0vitro","volume":"20","author":"Song CL","year":"2016","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"e_1_2_9_81_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.cellbio.12.1.697"},{"key":"e_1_2_9_82_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(96)79484-5"},{"key":"e_1_2_9_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.11.081"},{"key":"e_1_2_9_84_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0155829"},{"key":"e_1_2_9_85_1","doi-asserted-by":"publisher","DOI":"10.1089\/ten.tec.2012.0312"},{"key":"e_1_2_9_86_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.2526370"},{"key":"e_1_2_9_87_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.72.6.1202"},{"key":"e_1_2_9_88_1","first-page":"H298","article-title":"NO synthesis is involved in structural and functional effects of ACE inhibitors in injured arteries","volume":"270","author":"Belle E","year":"1996","journal-title":"Am J Physiol"},{"key":"e_1_2_9_89_1","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-200565080-00004"},{"key":"e_1_2_9_90_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.0000046233.94299.D6"},{"key":"e_1_2_9_91_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2013.11.024"},{"key":"e_1_2_9_92_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehr384"},{"key":"e_1_2_9_93_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)61455-0"},{"key":"e_1_2_9_94_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJV9I11A217"},{"key":"e_1_2_9_95_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJY14M07_11"},{"key":"e_1_2_9_96_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1509038"}],"container-title":["Journal of Cellular and Molecular Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjcmm.13936","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jcmm.13936","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T16:28:38Z","timestamp":1694795318000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jcmm.13936"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10,23]]},"references-count":95,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,1]]}},"alternative-id":["10.1111\/jcmm.13936"],"URL":"https:\/\/doi.org\/10.1111\/jcmm.13936","archive":["Portico"],"relation":{},"ISSN":["1582-1838","1582-4934"],"issn-type":[{"value":"1582-1838","type":"print"},{"value":"1582-4934","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,10,23]]},"assertion":[{"value":"2018-06-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-08-27","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-10-23","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}