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MIR100HG was firstly identified through a transcriptome analysis and found to regulate differentiation of human neural stem cells. It is functionally related with a number of signalling pathways such as TGF\u2010\u03b2, Wnt, Hippo and ERK\/MAPK signalling pathways. Dysregulation of MIR100HG has been detected in a diversity of cancers in association with clinical outcomes. Moreover, it has a role in the pathophysiology of dilated cardiomyopathy, intervertebral disk degeneration and pulmonary fibrosis. The current study summarizes the role of these lncRNAs in human disorders.<\/jats:p>","DOI":"10.1111\/jcmm.17875","type":"journal-article","created":{"date-parts":[[2023,7,24]],"date-time":"2023-07-24T18:14:45Z","timestamp":1690222485000},"page":"2278-2289","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["A concise review on the role of <scp>MIR100HG<\/scp> in human disorders"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0223-499X","authenticated-orcid":false,"given":"Soudeh","family":"Ghafouri\u2010Fard","sequence":"first","affiliation":[{"name":"Department of Medical Genetics, School of Medicine Shahid Beheshti University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atefeh","family":"Harsij","sequence":"additional","affiliation":[{"name":"Phytochemistry Research Centre Shahid Beheshti University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hossein","family":"Farahzadi","sequence":"additional","affiliation":[{"name":"Phytochemistry Research Centre Shahid Beheshti University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bashdar Mahmud","family":"Hussen","sequence":"additional","affiliation":[{"name":"Department of Clinical Analysis, College of Pharmacy Hawler Medical University  Erbil Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Taheri","sequence":"additional","affiliation":[{"name":"Urology and Nephrology Research Centre Shahid Beheshti University of Medical Sciences  Tehran Iran"},{"name":"Institute of Human Genetics Jena University Hospital  Jena Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Majid","family":"Mokhtari","sequence":"additional","affiliation":[{"name":"Skull Base Research Centre, Loghman Hakim Hospital Shahid Beheshti University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,7,24]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20225573"},{"issue":"3","key":"e_1_2_9_3_1","article-title":"One locus with two roles: microRNA\u2010independent functions of microRNA\u2010host\u2010gene locus\u2010encoded long noncoding RNAs. 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