{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T07:19:16Z","timestamp":1767165556548,"version":"build-2238731810"},"reference-count":48,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,12,5]],"date-time":"2023-12-05T00:00:00Z","timestamp":1701734400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100012553","name":"Chang Gung Memorial Hospital","doi-asserted-by":"publisher","award":["CMRPG3M0741"],"award-info":[{"award-number":["CMRPG3M0741"]}],"id":[{"id":"10.13039\/100012553","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["MOST111\u20102314\u2010B\u2010182A\u2010067\u2010MY3"],"award-info":[{"award-number":["MOST111\u20102314\u2010B\u2010182A\u2010067\u2010MY3"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012553","name":"Chang Gung Memorial Hospital","doi-asserted-by":"publisher","award":["XPRPG3M0181"],"award-info":[{"award-number":["XPRPG3M0181"]}],"id":[{"id":"10.13039\/100012553","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Cellular Molecular Medi"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    To evaluate the change of total antioxidant capacity (TAC) and ascorbic acid (AA) between femtosecond laser in\u00a0situ keratomileusis (FS\u2010LASIK) and laser\u2010assisted lenticule extraction (LALEX). A prospective non\u2010randomized study was conducted, and 33 and 75 eyes that had undergone FS\u2010LASIK or LALEX surgeries were enrolled, respectively. The tear films near corneal incisions were collected, and the concentrations of TAC and AA were determined. The generalized linear mixed model was adopted to calculate the adjusted odds ratio (aOR) with 95% confidence interval (CI) of TAC and AA between the two groups. The AA reduction was significant 1\u2009month after the LALEX and FS\u2010LASIK procedures (both\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.05), and the decrement in AA level was significantly larger in the FS\u2010LASIK group compared to the LALEX group (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.0002). In the subgroup analysis, the LALEX group demonstrated a lower decrement in TAC level in the individuals with dry eye disease (DED) than the FS\u2010LASIK group (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.0424), and the LALEX group demonstrated a significantly lower AA decrement in the participants with high myopia (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.0165) and DED (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.0043). The LALEX surgery causes lesser AA decrement compared to FS\u2010LASIK surgery especially for the patients with DED.\n                  <\/jats:p>","DOI":"10.1111\/jcmm.18069","type":"journal-article","created":{"date-parts":[[2023,12,5]],"date-time":"2023-12-05T13:08:56Z","timestamp":1701781736000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Differences in change of post\u2010operative antioxidant levels between laser\u2010assisted lenticule extraction and femtosecond laser in\u00a0situ keratomileusis"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1117-7878","authenticated-orcid":false,"given":"Hung\u2010Chi","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Chang Gung Memorial Hospital  Linkou Taiwan"},{"name":"Department of Medicine Chang Gung University College of Medicine  Taoyuan Taiwan"},{"name":"Center for Tissue Engineering 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Taiwan"},{"name":"Center for Tissue Engineering Chang Gung Memorial Hospital  Linkou Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing\u2010Yang","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Medical Research Chung Shan Medical University Hospital  Taichung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5639-0181","authenticated-orcid":false,"given":"Chao\u2010Kai","family":"Chang","sequence":"additional","affiliation":[{"name":"Nobel Eye Institute  Taipei Taiwan"},{"name":"Department of Optometry Da\u2010Yeh University  Chunghua 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