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Today, treating infections such as osteomyelitis is challenging due to the rise in drug\u2010resistant and biofilm\u2010forming pathogens. Therefore, researchers worldwide are seeking new ways to combat these infections. Nanotechnology, which is of interest in the medical field, has provided a platform for drug delivery and the treatment of osteomyelitis. Various biological, chemical, and physical methods are used for the biosynthesis of nanoparticles. Among these methods, biological methods, or green synthesis, are of great interest due to their non\u2010toxicity, high stability, low cost, and environmental friendliness. This study aimed to investigate nanoparticles biosynthesised from natural sources and use them for the treatment of osteomyelitis.<\/jats:p>","DOI":"10.1111\/jcmm.71003","type":"journal-article","created":{"date-parts":[[2025,12,25]],"date-time":"2025-12-25T14:25:47Z","timestamp":1766672747000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Nature Is a Valuable Source for the Biosynthesis of Nanoparticles and Their Effects on the Treatment of Osteomyelitis"],"prefix":"10.1111","volume":"29","author":[{"given":"Amir Reza","family":"Sadeghifar","sequence":"first","affiliation":[{"name":"Department of Orthopedics, School of Medicine Kerman University of Medical Sciences  Kerman Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alireza","family":"Farsinejad","sequence":"additional","affiliation":[{"name":"Stem Cells and Regenerative Medicine Innovation Center Kerman University of Medical Sciences  Kerman Iran"},{"name":"Department of Hematology and Medical Laboratory Sciences, Faculty of Allied Medicine Kerman University of Medical Sciences  Kerman Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naghmeh","family":"Satarzadeh","sequence":"additional","affiliation":[{"name":"Student Research Committee Kerman University of Medical Sciences  Kerman Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arman","family":"Shahabi","sequence":"additional","affiliation":[{"name":"Stem Cells and Regenerative Medicine Innovation Center Kerman University of Medical Sciences  Kerman Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8753-9599","authenticated-orcid":false,"given":"Amin","family":"Sadeghi Dousari","sequence":"additional","affiliation":[{"name":"Stem Cells and Regenerative Medicine Innovation Center Kerman University of Medical Sciences  Kerman Iran"},{"name":"Student Research Committee Kerman University of Medical Sciences  Kerman Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,12,25]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41413-022-00227-8"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1128\/cmr.00084\u201017"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cden.2016.12.001"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics14081563"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.micpath.2020.104431"},{"key":"e_1_2_10_7_1","volume-title":"StatPearls [Internet]","author":"Dobaria D. 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