{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T04:24:01Z","timestamp":1791087841281,"version":"4.1.0"},"reference-count":46,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,3,13]],"date-time":"2013-03-13T00:00:00Z","timestamp":1363132800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2013,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>The aim of this study was to assess the efficacy of mouthrinses formulations in oral malodour.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material &amp; Methods<\/jats:title><jats:p>This single\u2010centre, double\u2010blind, randomized, parallel group clinical trial compared the efficacy of Halita\u2122 and meridol<jats:sup>\u00ae<\/jats:sup> with and without zinc lactate versus negative and positive control. Volunteers with confirmed oral malodour (18\/group) rinsed with one mouthrinse during 7\u00a0days (15\u00a0ml, 2x\/day for 1\u00a0min.). 15\u00a0min. after a first rinse (masking effect), and after 7\u00a0days (therapeutic effect) the change in organoleptic scores and level of sulphur compounds was recorded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All rinses showed a masking effect (<jats:styled-content style=\"fixed-case\">OLS<\/jats:styled-content> 1 to 2 values reduced), only the rinses with antimicrobial ingredients showed a therapeutic effect (<jats:styled-content style=\"fixed-case\">OLS<\/jats:styled-content> 1 to 1.5 value less). The addition of zinc resulted in a more pronounced masking effect. Halita\u2122 and meridol<jats:sup>\u00ae<\/jats:sup> with zinc showed the best therapeutic effect.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Although the masking effect of the rinses can be attributed partially to a dilution and the effect of aromas, the therapeutic effect should be linked to the anti\u2010microbial action of active ingredients and counter action of zinc ions on <jats:styled-content style=\"fixed-case\">VSC<\/jats:styled-content>. A complete resolution of the unpleasant breath by additional mechanical intervention remains to be proven.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jcpe.12090","type":"journal-article","created":{"date-parts":[[2013,2,4]],"date-time":"2013-02-04T15:03:45Z","timestamp":1359990225000},"page":"505-513","source":"Crossref","is-referenced-by-count":33,"title":["Efficacy of different mouthrinse formulations in reducing oral malodour: a randomized clinical trial"],"prefix":"10.1111","volume":"40","author":[{"given":"Jesica","family":"Dadamio","sequence":"first","affiliation":[{"name":"Department of Periodontology Catholic University Leuven Leuven Belgium"},{"name":"Research Group for Microbial Adhesion Catholic University Leuven Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Van Tournout","sequence":"additional","affiliation":[{"name":"Department of Periodontology Catholic University Leuven Leuven 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