{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T09:16:03Z","timestamp":1761988563896},"reference-count":28,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,3,20]],"date-time":"2013-03-20T00:00:00Z","timestamp":1363737600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2013,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>In patients affected by periodontal disease, hypertension and systemic inflammation might cause an arterial hemodynamic derangement; this, in turn, can act as a mediator of the atherogenic process often seen in these patients. This study aimed at a comprehensive hemodynamic evaluation in periodontal patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Fourty\u2010eight subjects participating to a cardiovascular prevention programme were enrolled. Periodontitis, classical risk factors for atherosclerosis, and shear and tensile forces in both carotid and brachial arteries were evaluated. Calculated periodontal indexes were plaque, gingival and pocket deep (<jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content>) indexes. Simple and multiple regression analyses were performed. Afterwards, 30 of them with normal <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content> index were compared with 30 carefully \u2013 matched patients with periodontitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Brachial and carotid parietal tension were significantly associated with periodontal indexes, especially <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content>\u2010Sum, in both simple (<jats:italic>r<\/jats:italic>\u00a0=\u00a00.42, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001 for carotid artery and <jats:italic>r<\/jats:italic>\u00a0=\u00a00.36, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.02 for brachial artery) and multiple regression analyses. Shear stress gave similar results. In case\u2010control analysis, shear stress was lower by 15% and 30%, respectively, in carotid and brachial artery in patients with high <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content>; common carotid parietal tension was higher. Arterial stiffness resulted not associated with periodontitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Periodontal disease is associated to a complex atherosclerotic prone hemodynamic derangement, particularly in large elastic arteries.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jcpe.12099","type":"journal-article","created":{"date-parts":[[2013,2,22]],"date-time":"2013-02-22T05:53:10Z","timestamp":1361512390000},"page":"431-436","source":"Crossref","is-referenced-by-count":6,"title":["Common carotid and brachial artery hemodynamic alterations in periodontal disease"],"prefix":"10.1111","volume":"40","author":[{"given":"Claudio","family":"Carallo","sequence":"first","affiliation":[{"name":"Metabolic Diseases Unit Department of Clinical and Experimental Medicine \u201cMagna Gr\u00e6cia\u201d University Viale Europa 88100 Catanzaro Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Serena","family":"De Franceschi","sequence":"additional","affiliation":[{"name":"Metabolic Diseases Unit Department of Clinical and Experimental Medicine \u201cMagna Gr\u00e6cia\u201d University Viale Europa 88100 Catanzaro Italy"},{"name":"Institute of Dentistry \u201cMagna Gr\u00e6cia\u201d University Viale Europa 88100 Catanzaro Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cesare","family":"Tripolino","sequence":"additional","affiliation":[{"name":"Metabolic Diseases Unit Department of Clinical and Experimental Medicine \u201cMagna Gr\u00e6cia\u201d University Viale Europa 88100 Catanzaro Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michele","family":"Figliuzzi","sequence":"additional","affiliation":[{"name":"Institute of Dentistry \u201cMagna Gr\u00e6cia\u201d University Viale Europa 88100 Catanzaro Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Concetta","family":"Irace","sequence":"additional","affiliation":[{"name":"Metabolic Diseases Unit Department of Clinical and Experimental Medicine \u201cMagna Gr\u00e6cia\u201d University Viale Europa 88100 Catanzaro Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonzio","family":"Fortunato","sequence":"additional","affiliation":[{"name":"Institute of Dentistry \u201cMagna Gr\u00e6cia\u201d University Viale Europa 88100 Catanzaro Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agostino","family":"Gnasso","sequence":"additional","affiliation":[{"name":"Metabolic Diseases Unit Department of Clinical and Experimental Medicine \u201cMagna Gr\u00e6cia\u201d University Viale Europa 88100 Catanzaro Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,3,20]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.hjh.0000378634.97719.0b"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.0000078603.90302.4A"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2010.07.025"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.34.2.217"},{"key":"e_1_2_6_6_1","first-page":"109","volume-title":"Oral health care \u2010 prosthodontics, periodontology, biology, research and systemic conditions","author":"De Franceschi M. 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