{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T03:59:29Z","timestamp":1792036769465,"version":"4.4.0"},"reference-count":39,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2013,4,30]],"date-time":"2013-04-30T00:00:00Z","timestamp":1367280000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2013,7]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>A newly developed collagen matrix (CM<\/jats:styled-content>) of porcine origin has been shown to represent a potential alternative to palatal connective tissue grafts (CTG<\/jats:styled-content>) for the treatment of single Miller Class I and II<\/jats:styled-content> gingival recessions when used in conjunction with a coronally advanced flap (CAF<\/jats:styled-content>). However, at present it remains unknown to what extent CM<\/jats:styled-content> may represent a valuable alternative to CTG<\/jats:styled-content> in the treatment of Miller Class I<\/jats:styled-content> and II<\/jats:styled-content> multiple adjacent gingival recessions (MAGR<\/jats:styled-content>). The aim of this study was to compare the clinical outcomes following treatment of Miller Class I and II MAGR<\/jats:styled-content> using the modified coronally advanced tunnel technique (MCAT<\/jats:styled-content>) in conjunction with either CM<\/jats:styled-content> or CTG<\/jats:styled-content>.<\/jats:p><\/jats:sec>Methods<\/jats:title>Twenty\u2010two patients with a total of 156 Miller Class I and II<\/jats:styled-content> gingival recessions were included in this study. Recessions were randomly treated according to a split\u2010mouth design by means of MCAT<\/jats:styled-content>\u00a0+\u00a0CM<\/jats:styled-content> (test) or MCAT<\/jats:styled-content>\u00a0+\u00a0CTG<\/jats:styled-content> (control). The following measurements were recorded at baseline (i.e. prior to surgery) and at 12\u00a0months: Gingival Recession Depth (GRD<\/jats:styled-content>), Probing Pocket Depth (PD<\/jats:styled-content>), Clinical Attachment Level (CAL<\/jats:styled-content>), Keratinized Tissue Width (KTW<\/jats:styled-content>), Gingival Recession Width (GRW<\/jats:styled-content>) and Gingival Thickness (GT<\/jats:styled-content>). GT<\/jats:styled-content> was measured 3\u2010mm apical to the gingival margin. Patient acceptance was recorded using a Visual Analogue Scale (VAS<\/jats:styled-content>). The primary outcome variable was Complete Root Coverage (CRC<\/jats:styled-content>), secondary outcomes were Mean Root Coverage (MRC<\/jats:styled-content>), change in KTW<\/jats:styled-content>, GT<\/jats:styled-content>, patient acceptance and duration of surgery.<\/jats:p><\/jats:sec>Results<\/jats:title>Healing was uneventful in both groups. No adverse reactions at any of the sites were observed. At 12\u00a0months, both treatments resulted in statistically significant improvements of CRC<\/jats:styled-content>, MRC<\/jats:styled-content>, KTW<\/jats:styled-content> and GT<\/jats:styled-content> compared with baseline (p<\/jats:italic>\u00a0<\u00a00.05). CRC<\/jats:styled-content> was found at 42% of test sites and at 85% of control sites respectively (p<\/jats:italic>\u00a0<\u00a00.05). MRC<\/jats:styled-content> measured 71\u00a0\u00b1\u00a021%\u00a0mm at test sites versus<\/jats:italic> 90\u00a0\u00b1\u00a018% mm at control sites (p<\/jats:italic>\u00a0<\u00a00.05). Mean KTW<\/jats:styled-content> measured 2.4\u00a0\u00b1\u00a00.7\u00a0mm at test sites versus<\/jats:italic> 2.7\u00a0\u00b1\u00a00.8\u00a0mm at control sites (p<\/jats:italic>\u00a0>\u00a00.05). At test sites, GT<\/jats:styled-content> values changed from 0.8\u00a0\u00b1\u00a00.2 to 1.0\u00a0\u00b1\u00a00.3\u00a0mm, and at control sites from 0.8\u00a0\u00b1\u00a00.3 to 1.3\u00a0\u00b1\u00a00.4\u00a0mm (p<\/jats:italic>\u00a0<\u00a00.05). Duration of surgery and patient morbidity was statistically significantly lower in the test compared with the control group respectively (p<\/jats:italic>\u00a0<\u00a00.05).<\/jats:p><\/jats:sec>Conclusions<\/jats:title>The present findings indicate that the use of CM<\/jats:styled-content> may represent an alternative to CTG<\/jats:styled-content> by reducing surgical time and patient morbidity, but yielded lower CRC<\/jats:styled-content> than CTG<\/jats:styled-content> in the treatment of Miller Class I and II MAGR<\/jats:styled-content> when used in conjunction with MCAT<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jcpe.12112","type":"journal-article","created":{"date-parts":[[2013,4,18]],"date-time":"2013-04-18T06:18:48Z","timestamp":1366265928000},"page":"713-720","source":"Crossref","is-referenced-by-count":182,"title":["Treatment of multiple adjacent Miller class I and II<\/scp> gingival recessions with a Modified Coronally Advanced Tunnel (MCAT<\/scp>) technique and a collagen matrix or palatal connective tissue graft: a randomized, controlled clinical trial"],"prefix":"10.1111","volume":"40","author":[{"given":"Sofia","family":"Aroca","sequence":"first","affiliation":[{"name":"Department of Periodontology University of Bern Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B\u00e1lint","family":"Moln\u00e1r","sequence":"additional","affiliation":[{"name":"Department of Periodontology Semmelweis University Budapest Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P\u00e9ter","family":"Windisch","sequence":"additional","affiliation":[{"name":"Department of Periodontology Semmelweis University Budapest Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Istv\u00e1n","family":"Gera","sequence":"additional","affiliation":[{"name":"Department of Periodontology Semmelweis University Budapest Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni E.","family":"Salvi","sequence":"additional","affiliation":[{"name":"Department of Periodontology University of Bern Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitris","family":"Nikolidakis","sequence":"additional","affiliation":[{"name":"Private practice Viannou 1 Heraklion Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anton","family":"Sculean","sequence":"additional","affiliation":[{"name":"Department of Periodontology University of Bern Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,4,30]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2009.090122"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1992.tb01148.x"},{"key":"e_1_2_5_4_1","first-page":"216","article-title":"Use of the supraperiosteal envelope in soft tissue grafting for root coverage. 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