{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T10:28:21Z","timestamp":1783074501208,"version":"3.54.6"},"reference-count":52,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2013,6,25]],"date-time":"2013-06-25T00:00:00Z","timestamp":1372118400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2013,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To undertake cost\u2010effectiveness and cost\u2013benefit analyses of an intervention to improve oral health in patients presenting with the gingival manifestations of oral lichen planus (<jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials &amp; Methods<\/jats:title><jats:p>Eighty\u2010two patients were recruited to a 20\u2010week randomized controlled trial. The intervention was personalized plaque control comprising powered tooth brushing and inter\u2010dental cleaning advice. The primary outcome measure was the oral health impact profile (<jats:styled-content style=\"fixed-case\">OHIP<\/jats:styled-content>) with secondary outcomes of pain, plaque index, mucosal disease score and cost\u2010effectiveness. Private cost data and stated willingness\u2010to\u2010pay (<jats:styled-content style=\"fixed-case\">WTP<\/jats:styled-content>) values for treatment were obtained from intervention patients at 20\u00a0weeks.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall, 81% of intervention patients showed improvement in both plaque index and mucosal disease score at 20\u00a0weeks compared to 30% of controls that continued with their usual plaque control regimen. All intervention group patients stated a positive <jats:styled-content style=\"fixed-case\">WTP<\/jats:styled-content> value. The mean net value of the treatment was \u00a3172 compared to the incremental cost of the treatment estimated at \u00a3122.75. The cost\u2010effectiveness analysis resulted in an incremental cost\u2010effectiveness ratio of \u00a313 per <jats:styled-content style=\"fixed-case\">OHIP<\/jats:styled-content> point.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The tailored plaque control programme was more effective than control in treating the gingival manifestations of oral lichen planus. The programme is cost effective for modest values placed on a point on the <jats:styled-content style=\"fixed-case\">OHIP<\/jats:styled-content> scale and patients generally valued the treatment in excess of the cost.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jcpe.12126","type":"journal-article","created":{"date-parts":[[2013,5,21]],"date-time":"2013-05-21T07:49:34Z","timestamp":1369122574000},"page":"859-867","source":"Crossref","is-referenced-by-count":40,"title":["Cost\u2010effectiveness of personalized plaque control for managing the gingival manifestations of oral lichen planus: a randomized controlled study"],"prefix":"10.1111","volume":"40","author":[{"given":"Simon J.","family":"Stone","sequence":"first","affiliation":[{"name":"School of Dental Sciences Newcastle University Newcastle upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giles I.","family":"McCracken","sequence":"additional","affiliation":[{"name":"School of Dental Sciences Newcastle University Newcastle upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter A.","family":"Heasman","sequence":"additional","affiliation":[{"name":"School of Dental Sciences Newcastle University Newcastle upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konrad S.","family":"Staines","sequence":"additional","affiliation":[{"name":"School of Oral and Dental Sciences University of Bristol Bristol UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Pennington","sequence":"additional","affiliation":[{"name":"School of Oral and Dental Sciences University of Bristol Bristol UK"},{"name":"Department of Health Services Research and Policy London School of Hygiene and Tropical Medicine London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,6,25]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1109\/TAC.1974.1100705"},{"key":"e_1_2_7_3_1","doi-asserted-by":"crossref","first-page":"S25","DOI":"10.1016\/j.tripleo.2006.11.001","article-title":"Oral lichen planus and oral lichenoid lesions: diagnostic and therapeutic considerations","volume":"103","author":"Al\u2010Hashimi I.","year":"2007","journal-title":"Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0722.2009.00610.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/00220345870660110501"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0167-6296(87)90009-9"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10198-009-0168-z"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6963-6-96"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.2165\/00019053-199813050-00008"},{"key":"e_1_2_7_10_1","unstructured":"BSOM(2010)Guidelines for the management of oral lichen planus in secondary care. 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