{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T14:46:48Z","timestamp":1791470808101,"version":"4.3.4"},"reference-count":97,"publisher":"Wiley","issue":"s15","license":[{"start":{"date-parts":[[2014,3,19]],"date-time":"2014-03-19T00:00:00Z","timestamp":1395187200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2014,4]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n \n The aim of this Systematic Review (SR) was to assess the clinical efficacy of periodontal plastic surgery procedures in the treatment of localized gingival recessions (Rec) with or without inter\u2010dental clinical attachment loss (\n iCAL<\/jats:styled-content>\n ).\n <\/jats:p>\n <\/jats:sec>\n \n Material and Methods<\/jats:title>\n \n Electronic and hand searches were performed to identify randomized clinical trials (\n RCT<\/jats:styled-content>\n s) on treatment of single gingival recessions with at least 6\u00a0months of follow\u2010up. Primary outcome variable was complete root coverage (\n CRC<\/jats:styled-content>\n ). Secondary outcome variables were recession reduction (RecRed) and keratinized tissue (\n KT<\/jats:styled-content>\n ) gain. To evaluate treatment effect, Odds Ratios were combined for dichotomous data and mean differences in continuous data using a random\u2010effect model.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Fifty\u2010one\n RCT<\/jats:styled-content>\n s (53 articles) with a total of 1574 treated patients (1744 recessions) were included in this\n SR<\/jats:styled-content>\n . Finally, 30 groups of comparisons were identified and a total of 80 meta\u2010analyses were performed. Coronally Advanced Flap (\n CAF<\/jats:styled-content>\n ) was associated with higher probability of\n CRC<\/jats:styled-content>\n and higher amount of RecRed than Semilunar Coronal Positioned Flap (\n SCPF<\/jats:styled-content>\n ). The combination\n CAF<\/jats:styled-content>\n plus Connective Tissue Graft (\n CAF<\/jats:styled-content>\n +\n CTG<\/jats:styled-content>\n ) or\n CAF<\/jats:styled-content>\n plus Enamel Matrix Derivative (\n CAF<\/jats:styled-content>\n +\n EMD<\/jats:styled-content>\n ) was more effective than\n CAF<\/jats:styled-content>\n alone in terms of\n CRC<\/jats:styled-content>\n and RecRed. The combination\n CAF<\/jats:styled-content>\n plus Collagen Matrix (\n CAF<\/jats:styled-content>\n +\n CM<\/jats:styled-content>\n ) achieved higher RecRed than\n CAF<\/jats:styled-content>\n alone. In addition,\n CAF<\/jats:styled-content>\n +\n CTG<\/jats:styled-content>\n achieved\n CRC<\/jats:styled-content>\n more frequently than\n CAF<\/jats:styled-content>\n +\n EMD<\/jats:styled-content>\n ,\n SCPF<\/jats:styled-content>\n , Free Gingival Graft (\n FGG<\/jats:styled-content>\n ) and Laterally Positioned Flap (\n LPS<\/jats:styled-content>\n ).\n CAF<\/jats:styled-content>\n +\n CTG<\/jats:styled-content>\n was also associated with higher RecRed than Barrier Membranes (\n CAF<\/jats:styled-content>\n +\n GTR<\/jats:styled-content>\n ), CAF+EMD and\n CAF<\/jats:styled-content>\n +\n CM<\/jats:styled-content>\n .\n GTR<\/jats:styled-content>\n was not able to improve the clinical efficacy of\n CAF<\/jats:styled-content>\n . Studies adding Acellular Dermal Matrix (\n ADM<\/jats:styled-content>\n ) under\n CAF<\/jats:styled-content>\n showed a large heterogeneity and not significant benefits compared with\n CAF<\/jats:styled-content>\n alone. Multiple combinations, using more than a single graft\/biomaterial under the flap, usually provide similar or less benefits than simpler, control procedures in term of root coverage outcomes.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n CAF procedures alone or with CTG, EMD are supported by large evidence in modern periodontal plastic surgery. CAF+CTG achieved the best clinical outcomes in single gingival recessions with or without\n iCAL<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/jcpe.12182","type":"journal-article","created":{"date-parts":[[2014,3,19]],"date-time":"2014-03-19T03:14:56Z","timestamp":1395198896000},"source":"Crossref","is-referenced-by-count":289,"title":["Efficacy of periodontal plastic surgery procedures in the treatment of localized facial gingival recessions. 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